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AdipoGen Life Sciences
Vaspin (mouse) (rec.)
145
CHF
CHF 145.00
In stock
AG-40A-0094Y-C01010 µgCHF 145.00
AG-40A-0094Y-30103 x 10 µgCHF 290.00
Replaces AG-40A-0094
| Product Details | |
|---|---|
| Synonyms | Visceral Adipose Tissue-derived Serine Protease Inhibitor; Serpin A12; Visceral Adipose-specific Serpin |
| Product Type | Protein |
| Properties | |
| Source/Host | HEK 293 cells |
| Sequence |
Mouse vaspin (aa 21-413) is fused at the N-terminus to a FLAG®-tag. |
| Crossreactivity | Mouse |
| MW | ~55kDa (SDS-PAGE) |
| Purity | ≥95% (SDS-PAGE) |
| Endotoxin Content | <0.01EU/μg purified protein (LAL test). |
| Concentration | 0.1mg/ml after reconstitution. |
| Reconstitution | Reconstitute with 100μl sterile water. |
| Accession Number | Q7TMF5 |
| Formulation | Lyophilized. Contains PBS. |
| Other Product Data |
UniProt link Q7TMF5: Vaspin (mouse) FLAG is a registered trademark of Sigma-Aldrich Co. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. For maximum product recovery after thawing, centrifuge the vial before opening the cap. |
| Use/Stability |
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
Vaspin (Visceral adipose tissue-derived serpin; Serpin A12), a serine protease inhibitor (serpin), is an insulin-sensitizing adipocytokine that has been isolated from both visceral and subcutaneous white adipose tissue. Vaspin modulates insulin action by specifically inhibiting its target protease KLK7 in white adipose tissues. Based on recent findings, vaspin is suggested to regulate immune responses and inflammation and is correlated with various metabolic parameters. Vaspin may represent a novel biomarker for obesity and impaired insulin sensitivity and might serve as a new therapeutic target of metabolic syndrome.
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