AdipoGen Life Sciences

DNER (extracellular domain) (human):Fc (human) (rec.)

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AG-40A-0119T-C01010 µgCHF 170.00

AG-40A-0119T-C05050 µgCHF 470.00

Specifications / Handling

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Product Details
Synonyms	BET; UNQ262/PRO299; Delta and Notch-like Epidermal Growth Factor-related Receptor
Product Type	Protein
Properties
Source/Host	HEK 293 cells
Sequence	The extracellular domain of human DNER (aa 29-637) is fused at the C-terminus to the Fc portion of human IgG1.
Crossreactivity	Human
MW	~120kDa (SDS-PAGE)
Purity	≥90% (SDS-PAGE)
Endotoxin Content	<0.06EU/μg purified protein (LAL test; Lonza).
Concentration	After reconstitution: for 10µg size: 0.1mg/ml for 50µg size: 1 mg/ml
Reconstitution	10µg size: Reconstitute with 100µl sterile water. 50µg size: Reconstitute with 50µl sterile water.
Accession Number	NP_620711.3
Formulation	Lyophilized from 0.2μm-filtered solution in PBS.
Protein Negative Control	Fc (human) IgG1 Control (rec.)
Other Product Data	UniProt link NP_620711.3: DNER (human)
Shipping and Handling
Shipping	BLUE ICE
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0.1% BSA should be used for further dilutions.
Use/Stability	Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
Safety Data Sheet	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Product Description

DNER is an activator of the Notch1 pathway. It mediates neuron-glia interaction during astrocytogenesis.

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