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AdipoGen Life Sciences
Contactin-6 (human):Fc (human) (rec.)
215
CHF
CHF 215.00
In stock
AG-40A-0156-C01010 µgCHF 215.00
AG-40A-0156-C05050 µgCHF 540.00
Figure 1: Induction of Hes-1 with the treatment of hContactin-6-Fc.
A mouse preadpipocyte cell line, 3T3L1, was stimulated with 5μg/ml of hContactin-6-Fc (Prod. No. AG-40A-0156) as in indicated time points and each cell lysate was prepared and subjected to western blot by using anti-mouse Hes1 or GAPDH.
A mouse preadpipocyte cell line, 3T3L1, was stimulated with 5μg/ml of hContactin-6-Fc (Prod. No. AG-40A-0156) as in indicated time points and each cell lysate was prepared and subjected to western blot by using anti-mouse Hes1 or GAPDH.
| Product Details | |
|---|---|
| Synonyms | Neural Recognition Molecule NB-3; CNTN6 |
| Product Type | Protein |
| Properties | |
| Source/Host | HEK 293 cells |
| Sequence |
Human contactin-6 (aa 1-999) is fused at the C-terminus to the Fc portion of human IgG. |
| Crossreactivity | Human |
| Biological Activity |
Induces Hes-1 in 3T3L-1 cells. |
| MW | ~150kDa (SDS-PAGE) |
| Purity | ≥90% (SDS-PAGE) |
| Endotoxin Content | <0.1EU/μg purified protein (LAL test; Lonza). |
| Formulation | Liquid. 0.2μm-filtered solution in PBS. |
| Protein Negative Control | |
| Other Product Data |
UniProt link Q9UQ52: CNTN6 (human) |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap. |
| Use/Stability |
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
Contactin-6 is a member of the contactins, which mediate cell surface interactions during nervous system development. Contactin-6 has a key role in the formation of glutamatergic, but not GABAergic, synapses during postnatal development of the hippocampal formation as well as the cerebellum. It is involved in oligodendrocytes generation by acting as a ligand of Notch1. It is also involved in motor coordination.
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