Fc (human):Dectin-2 (mouse) (recombinant protein)

Specifications / Handling

More Information
Product Details
Synonyms	C-type Lectin Superfamily Member 10; Dendritic Cell-associated C-type Lectin 2; DC-associated C-type Lectin 2
Product Type	Protein
Properties
Source/Host	HEK 293 cells
Sequence	Mouse dectin-2 (aa 45-209) is fused at the C-terminus to the Fc portion of human IgG1.
Crossreactivity	Mouse
MW	~58kDa (SDS-PAGE)
Purity	≥95% (SDS-PAGE)
Endotoxin Content	<0.01EU/μg purified protein (LAL test).
Concentration	1mg/ml after reconstitution.
Reconstitution	Reconstitute with 50μl sterile water.
Formulation	Lyophilized. Contains PBS.
Protein Negative Control	Fc (human) IgG1 Control (rec.)
Other Product Data	UniProt link Q9JKF4: Dectin-2 (mouse)
Shipping and Handling
Shipping	BLUE ICE
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0.1% BSA should be used for further dilutions.
Use/Stability	Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
MSDS	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

Dectin-1 and dectin-2 are type II transmembrane proteins of the C-type lectin family. They contain single carbohydrate recognition domains (CRDs) in their extracellular region. Dectin-1 and dectin-2 are expressed in macrophages and dendritic cells. Dectin-1 recognizes β-glucans with its CRD and signals through its immunoreceptor tyrosine-based activation motif (ITAM)-like motif in the cytoplasmic domain, whereas dectin-2 recognizes α-mannans and transduces its signal through association with the ITAM-containing Fc receptor γ-chain.

Call	+41 61 926 6040
Fax	+41 61 926 6049

Fc (human):Dectin-2 (mouse) (rec.)