AdipoGen Life Sciences

Fc (human):Dectin-2 (mouse) (rec.)

CHF 350.00
In stock
AG-40B-0139-C05050 µgCHF 350.00
More Information
Product Details
Synonyms C-type Lectin Superfamily Member 10; Dendritic Cell-associated C-type Lectin 2; DC-associated C-type Lectin 2
Product Type Protein
Properties
Source/Host HEK 293 cells
Sequence

Mouse dectin-2 (aa 45-209) is fused at the C-terminus to the Fc portion of human IgG1.

Crossreactivity Mouse
MW ~58kDa (SDS-PAGE)
Purity ≥95% (SDS-PAGE)
Endotoxin Content <0.01EU/μg purified protein (LAL test).
Concentration 1mg/ml after reconstitution.
Reconstitution Reconstitute with 50μl sterile water.
Formulation Lyophilized. Contains PBS.
Protein Negative Control

Fc (human) IgG1 Control (rec.)

Other Product Data

UniProt link Q9JKF4: Dectin-2 (mouse)

Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice After reconstitution, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
Centrifuge lyophilized vial before opening and reconstitution.
PBS containing at least 0.1% BSA should be used for further dilutions.
Use/Stability Stable for at least 6 months after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description

Dectin-1 and dectin-2 are type II transmembrane proteins of the C-type lectin family. They contain single carbohydrate recognition domains (CRDs) in their extracellular region. Dectin-1 and dectin-2 are expressed in macrophages and dendritic cells. Dectin-1 recognizes β-glucans with its CRD and signals through its immunoreceptor tyrosine-based activation motif (ITAM)-like motif in the cytoplasmic domain, whereas dectin-2 recognizes α-mannans and transduces its signal through association with the ITAM-containing Fc receptor γ-chain.

© 2017 Adipogen Life Sciences. Pictures: © 2012 Martin Oeggerli. All Rights Reserved.