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AdipoGen Life Sciences
NAPRTase (B. subtilis) (rec.)
590
CHF
CHF 590.00
In stock
AG-40T-0104-C05050 µgCHF 590.00
| Product Details | |
|---|---|
| Synonyms | Nicotinate Phosphoribosyltransferase; pncB; yueK; EC 2.4.2.11 |
| Product Type | Protein |
| Properties | |
| Source/Host | E. coli |
| Sequence | Full-length NAPRTase (Bacillus subtilis). |
| Biological Activity | ~0.8 U/mg protein. One unit is defined as the amount of enzyme that synthesizes 1µmol nicotinic acid mononucleotide (NaMN) per min. |
| MW | ~56.0kDa |
| Purity | ≥98% (SDS-PAGE) |
| Endotoxin Content | N/A |
| Concentration | Lot specific |
| Formulation | Liquid. in 20mM TRIS-HCl, pH 7.8 containing 50mM sodium chloride. |
| Other Product Data | UniProt link O32090: NAPRTase (B. subtilis) |
| Shipping and Handling | |
| Shipping | DRY ICE |
| Short Term Storage | -20°C |
| Long Term Storage | -80°C |
| Handling Advice |
After opening, prepare aliquots and store at -80°C. Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 6 months after receipt when stored at -80°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
Nicotinate Phosphoribosyltransferase (NAPRTase) is involved in the biological processes of pyridine nucleotide biosynthesis and nicotinate nucleotide salvage and functions by catalyzing the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN). It is a crucial factor in the NAD+ biosynthesis pathway.
Catalytic activity: Β-nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-α-D-ribose 1-diphosphate.
Catalytic activity: Β-nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-α-D-ribose 1-diphosphate.
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