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AdipoGen Life Sciences
Adiponectin (rat) ELISA Kit
445
CHF
CHF 445.00
In stock
AG-45A-0005YEK-KI0196 wellsCHF 445.00
AG-45A-0005YTP-KI012 x 96 wellsCHF 780.00
Figure 1: Standard Curve
| Product Details | |
|---|---|
| Synonyms | ACRP30; AdipoQ; apM1; GBP28; Adipocyte complement related protein of 30kDa |
| Product Type | Kit |
| Properties | |
| Application Set | Quantitative ELISA |
| Specificity |
Detects rat adiponectin. Does not cross-react with mouse adiponectin, human adiponectin, rat resistin, rat RELM-α or rat leptin. |
| Crossreactivity | Rat |
| Quantity |
1 x 96 wells |
| Sensitivity | 50pg/ml |
| Range | 0.375 to 24ng/ml |
| Sample Type |
Cell Culture Supernatant Plasma Serum |
| Assay Type | Sandwich |
| Detection Type | Colorimetric |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice |
After standard reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Plate and reagents should reach room temperature before use. |
| Use/Stability | 12 months after the day of manufacturing. See expiry date on ELISA Kit box. |
| Documents | |
| Manual |
 Download PDF |
| MSDS |
Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
Adiponectin [ACRP30; AdipoQ] is a promising biomarker of insulin resistance and type 2 diabetes mellitus (T2DM) but also as a potential target for management of the metabolic syndrome. It is a very robust marker that is not prone to degradation or acute inflammatory challenges, is present in relatively high concentrations in the peripheral circulation, and can be collected by a variety of methods. The benefits of using adiponectin assays in clinical settings include, (a) prediction of risk of diabetes and metabolic status and (b) providing a tool to monitor metabolic improvements. Adiponectin exerts anti-atherogenic and anti-inflammatory properties and may be important as a biomarker for obesity-related cardiovascular disease (CVD). New findings showed urinary adiponectin excretion as an independent new biomarker of microvascular and macrovascular damage in T2DM and suggested it as a very promising tool for early cardiovascular disease risk assessment. Adiponectin serum level was also described as a good biomarker of colorectal adenoma, this being related to the positive correlation between obesity and increased risk of cancer at various sites (colorectal, breast, prostate and endometrium).
Product References
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- The Lou/C rat: A model of spontaneous food restriction associated with improved insulin sensitivity and decreased lipid storage in adipose tissue: C. Veyrat-Durebex, et al.; Am. J. Physiol. Endocrinol. Metab. 296, E1120 (2009)
- Subcutaneous adipose tissue-derived stem cells facilitate colonic mucosal recovery from 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced colitis in rats: Y. Ando, et al.; Inflamm. Bowel Dis. 14, 826 (2008)
- Effects of aerobic exercise training on visceral fat and serum adiponectin concentration in ovariectomized rats: A. Damirchi, et al.; Climacteric 13, 171 (2010)
- Adipose tissue explants and MDCK cells reciprocally regulate their morphogenesis in coculture: K. Udo, et al.; Kidney Int. 78, 60 (2010)
- The role of hypothalamic AMP-activated protein kinase in ovariectomy-induced obesity in rats: Y.C. Tsai, et al.; Menopause 17, 1194 (2010)
- Effects of ovariectomy and estrogen replacement therapy on visceral adipose tissue and serum adiponectin levels in rats: P. Babaei, et al.; Menopause Int. 16, 100 (2010)
- Antioxidant and Hepatoprotective Effects of Silibinin in a Rat Model of Nonalcoholic Steatohepatitis: Y. Haddad, et al.; Evid. Based Compl. Alternat. Med. 2011, nep164 (2011)
- High-fat diet and glucocorticoid treatment cause hyperglycemia associated with adiponectin receptor alterations: C. de Oliveira, et al.; Lipids Health Dis. 10, 11 (2011)
- Grape seed extract supplementation prevents high-fructose diet-induced insulin resistance in rats by improving insulin and adiponectin signalling pathways: A. Meeprom, et al.; Br. J. Nutr. 106, 1173 (2011)
- Effects of adrenal hormones on the expression of adiponectin and adiponectin receptors in adipose tissue, muscle and liver: C. de Oliveira, et al.; Steroids 76, 1260 (2011)
- Role of AMP-activated protein kinase and adiponectin during development of hepatic steatosis in high-fat diet-induced obesity in rats: S.K. Ha, et al.; J. Comp. Pathol. 145, 88 (2011)
- N-acetylcysteine and allopurinol synergistically enhance cardiac adiponectin content and reduce myocardial reperfusion injury in diabetic rats: T. Wang, et al.; PLoS One 6, e23967 (2011)
- NCX 1000 Alone or in Combination with Vitamin E Reverses Experimental Nonalcoholic Steatohepatitis in the Rat Similarly to UDCA: Y. Haddad, et al.; Int. J. Hepatol. 2011, 136816 (2011)
- Maternal prenatal undernutrition programs adipose tissue gene expression in adult male rat offspring under high-fat diet: M.A. Lukaszewski, et al.; AJPEM 301, E548 (2011)
- Melatonin protects steatotic and nonsteatotic liver grafts against cold ischemia and reperfusion injury: M.A. Zaoualí, et al.; J. Pineal. Res. 50, 213 (2011)
- Calorie Restriction with a High-Fat Diet Effectively Attenuated Inflammatory Response and Oxidative Stress-Related Markers in Obese Tissues of the High Diet Fed Rats: S. Park, et al.; Med. Inflamm. 2012, ID 984643 (2012)
- Increased secretion of insulin and proliferation of islet β-cells in rats with mesenteric lymph duct ligation: K. Nagino, et al.; BBRC 425, 266 (2012)
- Alpha-lipoic acid prevents non-alcoholic fatty liver disease in OLETF rats: T.S. Jung, et al.; Liver Int. 32, 1565 (2012)
- Selenium Significantly Inhibits Adipocyte Hypertrophy and Abdominal Fat Accumulation in OLETF Rats via Induction of Fatty Acid β-Oxidation: J.E. Kim, et al.; Biol. Trace Elem. Res. 150, 360 (2012)
- Aqueous extract of Liriope platyphylla, a traditional Chinese medicine, significantly inhibits abdominal fat accumulation and improves glucose regulation in OLETF type II diabetes model rats: J.E. Kim, et al.; Lab. Anim. Res. 28, 181 (2012)
- Daidzein improves insulin resistance in ovariectomized rats: Y.K. Cao, et al.; Climacteric 16, 111 (2013)
- Ambient fine particulate matter and ozone exposures induce inflammation in epicardial and perirenal adipose tissues in rats fed a high fructose diet: L. Sun, et al.; Part. Fibre Toxicol. 10, 43 (2013)
- Anthocyanin-rich juice lowers serum cholesterol, leptin, and resistin and improves plasma fatty acid composition in fischer rats: D. Graf, et al.; PLOS One 8, e66690 (2013)
- Taurine alleviates the progression of diabetic nephropathy in type 2 diabetic rat model: J.H. Koh, et al.; Int. J. Endocrinol. 2014, IS397307 (2014)
- Attenuation of carotid neointimal formation after direct delivery of a recombinant adenovirus expressing glucagon-like peptide-1 in diabetic rats: S. Lim, et al.; Cardiovasc. Res. 113, 183 (2017)
- Anti-obesity properties of the strain Bifidobacterium animalis subsp. lactis CECT 8145 in Zücker fatty rats: N.L. Carreras, et al.; Benef. Micr. 9, 629 (2018)
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