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AdipoGen Life Sciences
Amidepsine A
As low as
280
CHF
CHF 280.00
In stock
Only %1 left
AG-CN2-0109-M0011 mgCHF 280.00
AG-CN2-0109-MM252.5 mgCHF 580.00
![main product photo](https://adipogen.com/media/catalog/product/cache/5f03d36c884d3e04dc05d88be3541d8c/a/g/ag-cn2-0109.png)
Product Details | |
---|---|
Product Type | Chemical |
Properties | |
Formula |
C29H29NO11 |
MW | 567.6 |
CAS | 169181-28-6 |
Source/Host Chemicals | Isolated from Humcola sp. FO-2942. |
Purity Chemicals | ≥95% (HPLC) |
Appearance | Pale white powder. |
Solubility | Soluble in methanol, benzene or ethyl acetate. Insoluble in water or hexane. |
InChi Key | XQGKRCPZJSNFEL-UHFFFAOYSA-N |
Smiles | COC1=CC(OC)=C(C(=O)OC2=CC(C)=C(C(=O)OC3=CC(C)=C(C(=O)NC(C)C(O)=O)C(O)=C3)C(O)=C2)C(C)=C1 |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice | Keep cool and dry. |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS |
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Product Specification Sheet | |
Datasheet |
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Description
- Diacylglycerol acyltransferase (DGAT) inhibitor [1-4].
- Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.
Product References
- Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. I. Production, isolation and biological properties: H. Tomoda, et al.; J. Antibiot. 48, 937 (1995)
- Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. II. Structure elucidation of amidepsines A, B and C: H. Tomoda, et al.; J. Antibiot. 48, 942 (1995)
- Amidepsine E, an inhibitor of diacylglycerol acyltransferase produced by Humicola sp. FO-5969: H. Tomoda, et al.; J. Antibiot. 49, 929 (1996)
- Potential therapeutics for obesity and atherosclerosis: inhibitors of neutral lipid metabolism from microorganisms: H. Tomoda & S. Omura; Pharmacol. Ther. 115, 375 (2007)