Cookie Policy: This site uses cookies to improve your experience. You can find out more about our use of cookies in our Privacy Policy. By continuing to browse this site you agree to our use of cookies.
AdipoGen Life Sciences
Amidepsine A
280
CHF
CHF 280.00
In stock
AG-CN2-0109-M0011 mgCHF 280.00
AG-CN2-0109-MM252.5 mgCHF 580.00
| Product Details | |
|---|---|
| Product Type | Chemical |
| Properties | |
| Formula |
C29H29NO11 |
| MW | 567.6 |
| CAS | 169181-28-6 |
| Source/Host Chemicals | Isolated from Humcola sp. FO-2942. |
| Purity Chemicals | ≥95% (HPLC) |
| Appearance | Pale white powder. |
| Solubility | Soluble in methanol, benzene or ethyl acetate. Insoluble in water or hexane. |
| InChi Key | XQGKRCPZJSNFEL-UHFFFAOYSA-N |
| Smiles | COC1=CC(OC)=C(C(=O)OC2=CC(C)=C(C(=O)OC3=CC(C)=C(C(=O)NC(C)C(O)=O)C(O)=C3)C(O)=C2)C(C)=C1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Keep cool and dry. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Diacylglycerol acyltransferase (DGAT) inhibitor [1-4].
- Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.
Product References
- Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. I. Production, isolation and biological properties: H. Tomoda, et al.; J. Antibiot. 48, 937 (1995)
- Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. II. Structure elucidation of amidepsines A, B and C: H. Tomoda, et al.; J. Antibiot. 48, 942 (1995)
- Amidepsine E, an inhibitor of diacylglycerol acyltransferase produced by Humicola sp. FO-5969: H. Tomoda, et al.; J. Antibiot. 49, 929 (1996)
- Potential therapeutics for obesity and atherosclerosis: inhibitors of neutral lipid metabolism from microorganisms: H. Tomoda & S. Omura; Pharmacol. Ther. 115, 375 (2007)
Related Products
