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AdipoGen Life Sciences
Ambuic acid
80
CHF
CHF 80.00
In stock
AG-CN2-0129-C250250 µgCHF 80.00
AG-CN2-0129-M0011 mgCHF 240.00
| Product Details | |
|---|---|
| Synonyms | (+)-Ambuic acid |
| Product Type | Chemical |
| Properties | |
| Formula |
C19H26O6 |
| MW | 350.4 |
| CAS | 340774-69-8 |
| Source/Host Chemicals | Isolated from Pestalotiopsis sp. |
| Purity Chemicals | ≥95% (HPLC) |
| Appearance | Off-white solid. |
| Solubility | Soluble in DMSO, ethanol or methanol. |
| InChi Key | UDSQZJMGPSRCEM-HDKVZZTHSA-N |
| Smiles | CCCCC\C=C\C1=C(CO)[C@@H](O)[C@H]2O[C@@]2(C\C=C(/C)C(O)=O)C1=O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Keep cool and dry. |
| Use/Stability | Stable for at least 3 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Antibiotic.
- Antibacterial
- Antifungal.
- Inhibits the biosynthesis of cyclic peptide quormones in Gram-positive bacteria.
- Lead compound for antipathogenic drugs that target the quorum-sensing-mediated virulence expression of Gram-positive bacteria.
Product References
- Ambuic acid, a highly functionalized cyclohexenone with antifungal activity from Pestalotiopsis spp. and Monochaetia sp: J.Y. Li, et al.; Phytochemistry 56, 463 (2001)
- Ambuic acid inhibits the biosynthesis of cyclic peptide quormones in gram-positive bacteria: J. Nakayama, et al.; Antimicrob. Agents Chemother. 53, 580 (2009)
- Ambuic acid and torreyanic acid derivatives from the endolichenic fungus Pestalotiopsis sp.: G. Ding, et al.; J. Nat. Prod. 72, 182 (2009)
- Characterization of an Autoinducing Peptide Signal Reveals Highly Efficacious Synthetic Inhibitors and Activators of Quorum Sensing and Biofilm Formation in Listeria monocytogenes (2023): KHJ. West, et al.; Biochemistry 62, 2878 (2023)
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