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AdipoGen Life Sciences
Boromycin
140
CHF
CHF 140.00
In stock
AG-CN2-0166-C250250 µgCHF 140.00
AG-CN2-0166-M0011 mgCHF 390.00
| Product Details | |
|---|---|
| Synonyms | Antibiotic A 28829; Ivomycin; NSC216128 |
| Product Type | Chemical |
| Properties | |
| Formula |
C45H74BNO15 |
| MW | 879.9 |
| CAS | 34524-20-4 |
| Source/Host Chemicals | Isolated from Streptomyces sp. |
| Purity Chemicals | ≥99% (TLC) |
| Appearance | Off-white solid. |
| Solubility | Soluble in DMSO, ethanol or methanol. |
| InChi Key | OOBFYEMEQCZLJL-UWTAGDQBSA-O |
| Smiles | [H][C@@]12O[B-]34O[C@@H](C(=O)O[C@@]([H])(C\C=C/CC[C@H](O)C(C)(C)[C@]5([H])CC[C@@H](C)[C@@]1(O3)O5)[C@@H](C)OC(=O)[C@H]([NH3+])C(C)C)[C@]1(O4)O[C@@]([H])(CC[C@H]1C)C(C)(C)[C@H](O)CCC[C@@H]1C[C@H](OC2=O)[C@@H](C)O1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light. |
| Use/Stability |
Stable for at least 2 years after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Boron-containing macrolide antibiotic [1].
- Antibacterial [1].
- Antiprotozoal (Plasmodium, Babesia) [2].
- Anti-HIV compound [3,6].
- Ca2+ homeostasis modulator [4].
- Potentiator of bleomycin-induced anti-tumor activity [5].
- Used as a chiral selector in capillary electrophoresis [7].
Product References
- Structure of boromycin: J.D. Dunitz, et al.; Helv. Chim. Acta 54, 1709 (1971)
- Antibiotic A 28829: V. Prelog, et al.; US Patent 3,769,418 (1973)
- Boromycin, an anti-HIV antibiotic: J. Kohno, et al.; Biosci. Biotechnol. Biochem. 60, 1036 (1996)
- The effect of boromycin on the Ca2+ homeostasis: B. Lakatos, et al.; Mol. Cell Biochem. 231, 15 (2002)
- Boromycin abrogates bleomycin-induced G2 checkpoint: M. Arai, et al.; J. Antibiot. 57, 662 (2004)
- Biologically active compounds of semi-metals: T. Rezanka & K. Sigler; Phytochem. 69, 585 (2008) (Review)
- Study on the use of boromycin as a chiral selector in capillary electrophoresis: V. Maier, et al.; J. Chromatogr. A. 1237, 128 (2012)
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