AdipoGen Life Sciences

Citrinalin A

CHF 330.00

In stock

AG-CN2-0177-M0011 mgCHF 330.00

AG-CN2-0177-MM252.5 mgCHF 660.00

More Information
Product Details
Product Type	Chemical
Properties
Formula	C₂₅H₃₁N₃O₅
MW	453.5
CAS	1256635-19-4
Source/Host Chemicals	Isolated from fungus Penicillium sp.
Purity Chemicals	≥95% (HPLC)
Appearance	Pale yellow solid.
Solubility	Soluble in ethanol, methanol or DMSO (all 1mg/ml).
InChi Key	QVBARITWSQCBBV-UFMGCMQGSA-N
Smiles	O=C1NC2=C(C=CC(OC(C)(C)C3)=C2C3=O)[C@@]41C(C)(C)C(C[C@@](CCC5)([H])N5C6)[C@@]6([N+]([O-])=O)C4
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Keep cool and dry.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Description

Antibiotic. Mycotoxin. Showed no antimicrobial, antifungal or cytotoxic activity in initial tests, therefore the acitivty profile of this compound is not known so far.
Natural products that contain aliphatic nitro groups are extremely rare. In addition citrinalin A possesses three nitrogen atoms in chemically distinct environments which is rather unusual and therefore an attractive target for synthesis.
Pseudo-enantiomer of Cyclopiamine A.

Product References

Use of Experimental Design for the Optimization of the Production of New Secondary Metabolites by Two Penicillium Species: E.F. Pimenta, et al.; J. Nat. Prod. 73, 1821 (2010)
Total synthesis and isolation of citrinalin and cyclopiamine congeners: E.V. Mercado-Marin, et al.; Nature 509, 318 (2014)
Organic chemistry: Collaborative synthesis: J.L. Wood; Nature 509, 293 (2014)

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