AdipoGen Life Sciences

Ciglitazone

Name: Ciglitazone
Brand: AdipoGen Life Sciences
SKU: AG-CR1-0033
Price: 40.00 CHF
Availability: InStock

As low as CHF 40.00

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AG-CR1-0033-M0011 mgCHF 40.00

AG-CR1-0033-M0055 mgCHF 90.00

AG-CR1-0033-M02525 mgCHF 190.00

Specifications / Handling

More Information
Product Details
Synonyms	(±)-5-[4-(1-Methylcyclohexylmethoxy)benzyl]-thiazolidine-2,4-dione; U-63287
Product Type	Chemical
Properties
Formula	C₁₈H₂₃NO₃S
MW	333.5
CAS	74772-77-3
RTECS	XJ5813700
Purity Chemicals	≥98% (HPLC)
Appearance	Off-white solid.
Solubility	Soluble in DMSO or 100% ethanol.
Identity	Determined by ¹H-NMR.
Other Product Data	Stock solutions are stable for up to 3 months when stored at -20°C.
InChi Key	YZFWTZACSRHJQD-UHFFFAOYSA-N
Smiles	CC1(COC2=CC=C(CC3SC(=O)NC3=O)C=C2)CCCCC1
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	+4°C
Use/Stability	Stable for at least 2 years after receipt when stored at +4°C.
Documents
Safety Data Sheet	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Product Description

Product-specific References

The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones: T.M. Willson, et al.; J. Med. Chem. 39, 665 (1996)
Reduction of insulin resistance in obese and/or diabetic animals by 5-[4-(1-methylcyclohexylmethoxy)benzyl]-thiazolidine-2,4-dione (ADD-3878, U-63,287, ciglitazone), a new antidiabetic agent: T. Fujita, et al.; Diabetes 32, 804 (1983)
[[omega-(Heterocyclylamino)alkoxy]benzyl]-2,4-thiazolidinediones as potent antihyperglycemic agents: B.C. Cantello, et al.; J. Med. Chem. 37, 3977 (1994)
Peroxisome proliferator-activated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo: X. Xin, et al.; J. Biol. Chem. 274, 9116 (1999)
The thiazolidinedione ciglitazone reduces bacterial outgrowth and early inflammation during Streptococcus pneumoniae pneumonia in mice: M.E. Stegenga, et al.; Crit. Care Med. 37, 614 (2009)
Ciglitazone, a novel inhibitor of lung apoptosis following hemorrhagic shock: R.S. Chima, et al.; Int. J. Clin. Exp. Med. 3, 1 (2010)

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