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AdipoGen Life Sciences
Thioglycine
110
CHF
CHF 110.00
In stock
AG-CR1-3530-M0011 mgCHF 110.00
AG-CR1-3530-M0055 mgCHF 440.00
| Product Details | |
|---|---|
| Synonyms | 2-Aminoethanethioic S-acid; Aminothioacetic acid |
| Product Type | Chemical |
| Properties | |
| Formula |
C2H5NOS |
| MW | 91.1 |
| CAS | 758-10-1 |
| Purity Chemicals | ≥98% (NMR) |
| Appearance | White solid. |
| Solubility | Soluble in DMSO (10mg/ml) or water. |
| Identity | Determined by 1H-NMR. |
| InChi Key | CYFJIBWZIQDUSZ-UHFFFAOYSA-N |
| Smiles | NCC(S)=O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Non-toxic hydrogen sulfide (H2S) donor in vitro and in vivo. Stable under acidic and basic conditions but in the presence of bicarbonate liberates the gasotransmitter H2S and glycine.
- In cells it enhances cGMP formation and in mouse aortic rings promotes vasorelaxation.
- Cardioprotective agent.
Product References
- Characterization of thioglycine, a water-soluble hydrogen sulfide (H2S) donor: Z. Zhou, et al.; Vasc. Pharmacol. 56, 356 (2012)
- Thioglycine and L-thiovaline: biologically active H2S-donors: Z. Zhou, et al. Bioorg. Med. Chem. 20, 2675 (2012)
- Thioglycine, a slow-releasing H2S donor, exerts cardioprotection in anesthetized rabbits through activation of Akt kinase: S.I. Bibli, et al.; Eur. Heart J. 34 (Suppl. 1), P5535 (2013)
- Hydrogen sulfide (H2S) releasing agents: chemistry and biological applications: Y. Zhao, et al.; Chem. Commun. 50, 11788 (2014)
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