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Chemodex
WSP1
Product Details | |
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Synonyms | 3'-Methoxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-6'-yl 2-(pyridin-2-yldisulfanyl)benzoate; Washington State Probe-1 |
Product Type | Chemical |
Properties | |
Formula |
C33H21NO6S2 |
MW | 591.65 |
CAS | 1352750-34-5 |
Source/Host Chemicals | Synthetic |
Purity Chemicals | ≥97% (NMR) |
Appearance | Off-white to yellow powder |
Solubility | Soluble in DMSO (2 mg/ml) or DMF (20 mg/ml). |
Identity | Determined by NMR. |
Declaration | Manufactured by Chemodex. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | VHKQAUGSGQUCDU-UHFFFAOYSA-N |
Smiles | COC1=CC=C2C(OC3=CC(OC(=O)C4=CC=CC=C4SSC4=CC=CC=N4)=CC=C3C22OC(=O)C3=C2C=CC=C3)=C1 |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice |
Keep cool and dry. Protect from light and moisture. |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS | Inquire |
Product Specification Sheet | |
Datasheet | Download PDF |
Hydrogen sulfide (H2S) is an important gaseous mediator, like nitric oxide, that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. WSP-1 is a reactive disulfide-containing, fluorescent probe designed to detect H2S in biological samples and cells. Through a reaction-based fluorescent turn-on strategy, WSP-1 selectively and rapidly reacts with H2S to generate benzodithiolone and a fluorophore with excitation and emission maxima of 465 and 515 nm, respectively.
(1) C. Liu, et al.; Angew. Chem. Int. Ed. Engl. 50, 10327 (2011)