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Ancell
anti-CD66b (human), mAb (ANC1D5) (preservative free)
306
CHF
CHF 306.00
In stock
ANC-217-820100 µgCHF 306.00
| Product Details | |
|---|---|
| Synonyms | CEACAM8; Carcinoembryonic Antigen-related Cell Adhesion Molecule 8 |
| Product Type | Monoclonal Antibody |
| Properties | |
| Clone | ANC1D5 |
| Isotype | Mouse IgG1κ |
| Source/Host | Purified from concentrated hybridoma tissue culture supernatant. |
| Immunogen/Antigen | Recombinant soluble human CD66b. |
| Label/Conjugates | Preservative Free |
| Application |
ELISA (Detection) |
| Crossreactivity | Human |
| Specificity |
Binds to CD66b on the cell surface of human PMN in flow cytometry and detects recombinant human CD66b in sandwich EIA utilizing either clone ANC4A4(Cat #ANC-220-020) or ANC3C5(Cat# ANC-219-020) as a capture reagent. May cross-react with other CD66 isoforms, as it also binds to the cell surface of an epithelial tumor line. |
| Purity | ≥95% (SDS-PAGE) |
| Purity Detail | Protein A purified. |
| Concentration | 1mg/ml |
| Formulation | 50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl. |
| Isotype Negative Control | |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Accession Number | P31997 |
| Declaration | Manufactured by Ancell Corporation. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice |
Avoid freeze/thaw cycles. Keep sterile. |
| Use/Stability | Stable for at least 1 year after receipt when stored at +4°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Human CD66b (CEACAM8, CGMb, NCA-95, CD67) is a 95kD member of the Carcinoembryonic Antigen (CEA) group. It is expressed on granulocytes and functions as an adhesion molecule. Similar to the CD66 a, c, and d isoforms, engagement of CD66b on neutrophils causes increased adhesion to endothelial cells. Crosslinking CD66b on neutrophils with antibodies triggers IL-8 release.
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