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Ancell
anti-CD66b (human), mAb (ANC3C5) (preservative free)
306
CHF
CHF 306.00
In stock
ANC-219-820100 µgCHF 306.00
| Product Details | |
|---|---|
| Synonyms | CEACAM8; Carcinoembryonic Antigen-related Cell Adhesion Molecule 8 |
| Product Type | Monoclonal Antibody |
| Properties | |
| Clone | ANC3C5 |
| Isotype | Mouse IgG1κ |
| Source/Host | Purified from concentrated hybridoma tissue culture supernatant. |
| Immunogen/Antigen | Recombinant soluble human CD66b. |
| Label/Conjugates | Preservative Free |
| Application |
ELISA (Capture or Detection) |
| Crossreactivity | Human |
| Specificity |
Binds to CD66b on the cell surface of human PMN in flow cytometry and works as an EIA capture or detection reagent for recombinant human CD66b when paired with clone ANC4A4 (Cat #ANC-220-020). |
| Purity | ≥95% (SDS-PAGE) |
| Purity Detail | Protein A purified. |
| Concentration | 1mg/ml |
| Formulation | 50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl. |
| Isotype Negative Control | |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Accession Number | P31997 |
| Declaration | Manufactured by Ancell Corporation. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice |
Avoid freeze/thaw cycles. Keep sterile. |
| Use/Stability | Stable for at least 1 year after receipt when stored at +4°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Human CD66b (CEACAM8, CGMb, NCA-95, CD67) is a 95kD member of the Carcinoembryonic Antigen (CEA) group. It is expressed on granulocytes and functions as an adhesion molecule. Similar to the CD66 a, c, and d isoforms, engagement of CD66b on neutrophils causes increased adhesion to endothelial cells. Crosslinking CD66b on neutrophils with antibodies triggers IL-8 release.
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