anti-CD275 [B7-H2] (human), mAb (ANC4E3) (preservative free)

CHF 306.00
In stock
ANC-263-820100 µgCHF 306.00
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Product Details
Synonyms B7-H2; ICOS Ligand; B7-like Protein Gl50; B7RP-1
Product Type Monoclonal Antibody
Clone ANC4E3
Isotype Mouse IgG1κ
Immunogen/Antigen Human Raji cells, recombinant human CD275-muIg.
Label/Conjugates Preservative Free


Crossreactivity Human
Formulation 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl
Isotype Negative Control

Mouse IgG1 Isotype Control (preservative free)

Other Product Data

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Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by Ancell Corporation.
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Avoid freeze/thaw cycles.
Use/Stability Stable for at least 1 year after receipt when stored at +4°C.
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Product Specification Sheet
Datasheet Download PDF

The inducible costimulator CD278 (ICOS) is similar to human CD28 (24% homology) and plays an analogous role in the T cell activation process. Signaling through CD278 is particularly important in progression of TH2 immune response. The receptor for human CD278 (ICOS) is CD275 (GL50), a member of the B7 family sharing ~20% homology with CD80 (B7-1) and CD86 (B7-2). Blockade of the CD278-CD275 interaction in mice improves allograft survival and reduces EAE.

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