Ancell

CD275 [B7-H2] (human)-muIg Fusion Protein (Biotin)

CHF 669.00

In stock

ANC-575-03025 µgCHF 669.00

More Information
Product Details
Product Type	Protein
Properties
Source/Host	CHO cells
Application	Flow Cytometry ELISA
Label/Conjugates	Biotin
Formulation	50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative).
Protein Negative Control	MuIg Control Protein (Biotin)
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
Declaration	Manufactured by Ancell Corporation.
Shipping and Handling
Shipping	BLUE ICE
Short Term Storage	+4°C
Long Term Storage	+4°C
Handling Advice	Avoid freeze/thaw cycles.
Use/Stability	Stable for at least 6 months after receipt when stored at +4°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

The inducible costimulator CD278 (ICOS) is similar to human CD28 (24% homology), and plays an analogous role in the T cell activation process. Signaling through CD278 is particularly important in progression of TH2 immune response. The receptor for human CD278 (ICOS) is CD275 (GL50), a member of the B7 family sharing ~20% homology with CD80 (B7-1) and CD86 (B7-2). Blockade of the CD278-CD275 interaction in mice improves allograft survival and reduces EAE.

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