anti-CD275 [B7-H2] (human), mAb (ANC4E3) (Biotin)

CHF 352.00
In stock
ANC-263-030100 µgCHF 352.00
More Information
Product Details
Synonyms B7-H2; ICOS Ligand; B7-like Protein Gl50; B7RP-1
Product Type Monoclonal Antibody
Properties
Clone ANC4E3
Isotype Mouse IgG1κ
Immunogen/Antigen Human Raji cells, recombinant human CD275-muIg.
Label/Conjugates Biotin
Application

ELISA

Crossreactivity Human
Formulation 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative).
Isotype Negative Control

Mouse IgG1 Isotype Control (Biotin)

Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by Ancell Corporation.
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Avoid freeze/thaw cycles.
Use/Stability Stable for at least 1 year after receipt when stored at +4°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

The inducible costimulator CD278 (ICOS) is similar to human CD28 (24% homology) and plays an analogous role in the T cell activation process. Signaling through CD278 is particularly important in progression of TH2 immune response. The receptor for human CD278 (ICOS) is CD275 (GL50), a member of the B7 family sharing ~20% homology with CD80 (B7-1) and CD86 (B7-2). Blockade of the CD278-CD275 interaction in mice improves allograft survival and reduces EAE.

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