Ancell

anti-CD278 [ICOS] (human), mAb (ANC6C6) (Biotin)

CHF 423.00

In stock

ANC-265-030100 µgCHF 423.00

More Information
Product Details
Synonyms	ICOS; Inducible T Cell Costimulator; CRP1; CD28-related Protein-1; AILIM
Product Type	Monoclonal Antibody
Properties
Clone	ANC6C6
Isotype	Mouse IgG1κ
Immunogen/Antigen	Human HPB-MLT cells, recombinant human CD278(ICOS)-muIg.
Label/Conjugates	Biotin
Application	ELISA Flow Cytometry Functional Application
Crossreactivity	Human
Formulation	50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative).
Isotype Negative Control	Mouse IgG1 Isotype Control (Biotin)
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
Declaration	Manufactured by Ancell Corporation.
Shipping and Handling
Shipping	BLUE ICE
Short Term Storage	+4°C
Long Term Storage	+4°C
Handling Advice	Avoid freeze/thaw cycles.
Use/Stability	Stable for at least 1 year after receipt when stored at +4°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

The inducible costimulator CD278 (ICOS) is similar to human CD28 (24% homology) and plays an analogous role in the T cell activation process. Secondary signaling through CD28 or CD278 results in discrete cytokine secretion profiles by the activated T cells. CD275 (ICOSL; GL50; B7-H2) has been shown to be the ligand for CD278 (ICOS).

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