anti-CD40 (human), mAb (EA-5) (R-PE)

CHF 319.00
In stock
ANC-300-050120 testsCHF 319.00
More Information
Product Details
Synonyms CD40L Receptor; CDw40; Tumor Necrosis Factor Receptor Superfamily Member 5; TNFRSF5
Product Type Monoclonal Antibody
Properties
Clone EA-5
Isotype Mouse IgG1
Immunogen/Antigen Murine L cells transfectants expressing human CD40.
Label/Conjugates R-PE
Application

ELISA
Flow Cytometry
Functional Application

Crossreactivity Human
Rat
Formulation 50 mM Sodium Phosphate pH 7.5, 500 mM Potassium Chloride, 150mM NaCl, 15% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative).
Isotype Negative Control

Mouse IgG1 Isotype Control (R-PE)

Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by Ancell Corporation.
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Do not freeze.
Use/Stability Stable for at least 1 year after receipt when stored at +4°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

CD40 belongs to the TNF-receptor superfamily and is essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development and germinal center formation. The interaction of CD40-CD40L is necessary for amyloid-β-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is constitutively expressed by antigen presenting cells, including dendritic cells, B cells and macrophages. Consistent with its widespread expression on normal cells, CD40 is also expressed on a wide range of tumor cells, including non-Hodgkin's and Hodgkin's lymphomas, myeloma and some carcinomas including nasopharynx, bladder, cervix, kidney and ovary.

© 2017 Adipogen Life Sciences. Pictures: © 2012 Martin Oeggerli. All Rights Reserved.