Ancell

anti-CD155 (PVR) (human), mAb (ANC6A3) (R-PE)

CHF 520.00

In stock

ANC-350-050120 testsCHF 520.00

More Information
Product Details
Synonyms	PVR; Polio Virus Receptor
Product Type	Monoclonal Antibody
Properties
Clone	ANC6A3
Isotype	Mouse IgG1κ
Immunogen/Antigen	Recombinant human CD155.
Label/Conjugates	R-PE
Application	ELISA FACS: Working Dilution 1:50
Crossreactivity	Human
Specificity	Binds to cell surface CD155 on U-937 cells and to recombinant CD155 in ELISA assay. The antibody clones ANC6A3 and ANC2B2 (#ANC-255-020) bind to distict epitopes of CD155 and are suitable as a matched pair for a sandwich ELISA assay.
Purity	≥95% (SDS-PAGE)
Purity Detail	Protein A purified.
Concentration	0.5mg/ml
Formulation	50mM Sodium Phosphate pH 7.5, 500mM Potassium Chloride, 150mM NaCl, 15% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative).
Isotype Negative Control	Mouse IgG1 Isotype Control (R-PE)
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
Declaration	Manufactured by Ancell Corporation.
Shipping and Handling
Shipping	BLUE ICE
Short Term Storage	+4°C
Long Term Storage	+4°C
Handling Advice	Avoid freeze/thaw cycles. Protect from light.
Use/Stability	Stable for at least 1 year after receipt when stored at +4°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

Human CD155 (Polio Virus Receptor, PVR, Necl-5) is a 70 kd type I Ig superfamily molecule. It is involved in formation of intracellular junctions between epithelial cells. Its ligands include CD226 (DNAM-1), and CD96 (TACTILE). CD155 expression by tumor has been shown to be upregulated by nitric oxide. A soluble version of CD155 has been shown to exist. High CD155 expression has recently been exploited to use engineered poliovirus to treat glioblastoma.

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