CD278 [ICOS] (human)-muIg Fusion Protein (R-PE)
|Synonyms||ICOS; Inducible T Cell Costimulator; CRP1; CD28-related Protein-1; AILIM|
|Formulation||50mM Sodium Phosphate pH 7.5, 500mM Potassium Chloride, 150mM NaCl, 15% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative).|
|Protein Negative Control|
|Other Product Data||
Click here for Original Manufacturer Product Datasheet
|Declaration||Manufactured by Ancell Corporation.|
|Shipping and Handling|
|Short Term Storage||+4°C|
|Long Term Storage||+4°C|
Do not freeze.
Protect from light.
|Use/Stability||Stable for at least 1 year after receipt when stored at +4°C.|
|Product Specification Sheet|
The inducible costimulator CD278 (ICOS; T cell activation molecule H4) is similar to human CD28 (24% homology) and plays an analogous role in the T cell activation process. Each secondary signal from CD278 results in a discrete cytokine secretion profile displayed by the activated T cell. Both activation processes are effectively down regulated by CD152 (CTLA-4) engagement.