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Ancell
CD271 [NGFR] (human)-muIg Fusion Protein
551
CHF
CHF 551.00
In stock
ANC-527-02025 µgCHF 551.00
Product Details | |
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Synonyms | Low-affinity Neurotrophin Receptor p75NTR; Low-affinity Nerve Growth Factor Receptor; Tumor Necrosis Factor Receptor Superfamily Member 16; TNFRSF16 |
Product Type | Protein |
Properties | |
Source/Host | CHO cells |
Application |
ELISA |
Formulation | 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5mg/ml Gentamicin sulfate |
Protein Negative Control | |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
Declaration | Manufactured by Ancell Corporation. |
Shipping and Handling | |
Shipping | BLUE ICE |
Short Term Storage | +4°C |
Long Term Storage | +4°C |
Handling Advice | Avoid freeze/thaw cycles. |
Use/Stability | Stable for at least 6 months after receipt when stored at +4°C. |
Documents | |
MSDS | Inquire |
Product Specification Sheet | |
Datasheet | Download PDF |
Description
CD271 (p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR; NGFR) is a type I transmembrane protein, expressed by many cell types including neurons, Schwann cells, mesenchymal stem/stromal cells, follicular dendritic cells and melanocytes. The extracellular portion contains four TNFR-Cys repeats that form the binding domain for its ligands, (NGF, BDNF, NTF3 and NTF4). The intracellular portion of CD271 contains a death domain, which interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9, to promote cell apoptosis and to regulate cell differentiation and neurogenesis.