Ancell

CD271 [NGRF] (human)-muIg Fusion Protein (preservative free)

CHF 551.00

In stock

ANC-527-82025 µgCHF 551.00

More Information
Product Details
Synonyms	Low-affinity Neurotrophin Receptor p75NTR; Low-affinity Nerve Growth Factor Receptor; Tumor Necrosis Factor Receptor Superfamily Member 16; TNFRSF16
Product Type	Protein
Properties
Source/Host	CHO cells
Application	ELISA
Label/Conjugates	Preservative Free
Formulation	50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl
Protein Negative Control	MuIg Control Protein (preservative free)
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
Declaration	Manufactured by Ancell Corporation.
Shipping and Handling
Shipping	BLUE ICE
Short Term Storage	+4°C
Long Term Storage	+4°C
Handling Advice	Avoid freeze/thaw cycles.
Use/Stability	Stable for at least 6 months after receipt when stored at +4°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

CD271 (p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR; NGFR) is a type I transmembrane protein, expressed by many cell types including neurons, Schwann cells, mesenchymal stem/stromal cells, follicular dendritic cells and melanocytes. The extracellular portion contains four TNFR-Cys repeats that form the binding domain for its ligands, (NGF, BDNF, NTF3 and NTF4). The intracellular portion of CD271 contains a death domain, which interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9, to promote cell apoptosis and to regulate cell differentiation and neurogenesis.

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