BellBrook

Enzolution™ WRN Helicase TR-FRET Assay System

CHF 0.00
In stock
BBL-3032-TR-1K1000 assaysCHF 726.00
BBL-3032-TR-10K10000 assaysCHF 2'609.00
BBL-3032-TR-100K10 x 10000 assaysINQ
More Information
Product Details
Synonyms Werner Syndrome Protein; Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN; DNA Helicase RecQ-like Type 3; RecQ Protein-like 2
Product Type Kit
Properties
Application Set Compound Screening
Crossreactivity Human
Quantity

1000 assays/384wells (BBL-3032TR-1K)

10000 assays/384wells (BBL-3032TR-10K)

100000 assays/384wells (BBL-3032TR-100K)

Note: The exact number of assays depends on enzyme reaction conditions.

Detection Type TR-FRET
Kit Contains

- WRN helicase enzyme (human) (rec.) (His)
- WRN-H DNA Substrate
- WRN Assay Buffer 10X
- 384-Well Low Volume Assay Plates (Corning#4513; sold under #BBL-2231 or BBL-2232)

Other Product Data

Click here for Complete Information from the Original Manufacturer
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by BellBrook Labs.
Accession Number Q14191
Shipping and Handling
Shipping DRY ICE
Short Term Storage -20°C
Long Term Storage -20°C
Handling Advice Avoid freeze/thaw cycles.
Documents
Manual Download PDF
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF
Description

WRN helicase inhibitors are sought-after therapeutics for targeting cancers that lack adequate mismatch repair machinery and enhanced mutation at microsatellite repeats (MSI-H). The WRN Helicase Assay System, when used with the Transcreener ADP Assay Kit, provides all reagents required to screen and profile WRN helicase inhibitors.

The WRN Helicase Assay System includes WRN helicase (Werner syndrome helicase) enzyme, substrate, assay plates, and buffers required to measure WRN Helicase's ATPase activity. The Transcreener ADP Assay (sold separately), a far-red competitive assay designed for HTS and inhibitor dose-response measurements, measures ADP produced to determine enzymatic activity. 

When purchasing the WRN helicase assay system, it is important to choose the assay system readout corresponding to the TR-FRET configuration of your Transcreener ADP Assay Kit!

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