BioViotica

Isatropolone A

CHF 145.00
In stock
BVT-0080-M0011 mgCHF 145.00
BVT-0080-M0055 mgCHF 430.00
More Information
Product Details
Product Type Chemical
Properties
Formula

C24H24O9

MW 456.5
Source/Host Chemicals Isolated from Streptomyces rubiginosohelvolus Gö66.
Purity Chemicals ≥98% (HPLC)
Appearance Orange powder.
Solubility Soluble in DMSO, chloroform or dichloromethane.
Identity Determined by 1H-NMR.
Declaration Manufactured by BioViotica.
InChi Key GPTONKSPQNETHU-DLIRKSNVSA-N
Smiles [H][C@]12OC3=C(C(=O)C=C4C(=O)C(C(=O)CCC)=C5C=C(C)OC3=C45)[C@@]1(O)[C@H](O)[C@H](OC)[C@@H](C)O2
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light when in solution.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
After reconstitution protect from light at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description
  • Antileishmanial agent. Active against Leishmania donovani, the causative agent of visceral leishmaniasis. Showed no activity against intracellular Leishmania.
  • Amine-reactive fluorescent compound.
  • Cytostatic.
  • Weak cytotoxic (3-10 μM).
Product References
  1. Isolierung, Strukturaufklärung und Biosynthese der Isatropolone aus Streptomyces sp. Gö66: N. Pöhlmann; PhD Thesis; Univ. Göttingen, Cuvillier Verlag, Page 1-136 (2004) [ISBN 3-86537-286-4]
  2. Structure and biosynthesis of isatropolones, bioactive amine-scavenging fluorescent natural products from Streptomyces Gö66: X. Cai, et al.; Angew. Chem. Int. Ed. Engl. 56, 4945 (2017)
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