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BioViotica
Aurantimycin A
95
CHF
CHF 95.00
In stock
BVT-0398-M0011 mgCHF 95.00
| Product Details | |
|---|---|
| Product Type | Chemical |
| Properties | |
| Formula |
C38H64N8O14 |
| MW | 857.0 |
| CAS | 162478-50-4 |
| Source/Host Chemicals | Isolated from Streptomyces aurantiacus JA 4570. |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | Off-white solid. |
| Solubility | Soluble in chloroform, dichloromethane or DMSO. Poorly soluble in water. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by BioViotica. |
| InChi Key | JSVPJXYQXDNLRD-NSCUIBACSA-N |
| Smiles | [H][C@@]12CCCNN1C(=O)CNC(=O)[C@H](COC)N(O)C(=O)[C@@]1([H])CCCNN1C(=O)[C@@H](NC(=O)[C@](C)(O)[C@]1(O)CC[C@@H](CC(C)C)[C@H](C)O1)[C@@H](OC(=O)[C@@H](C)N(O)C2=O)C(C)C |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Keep cool and dry. |
| Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Depsipeptide antibiotic.
- Active against Gram-positive bacteria.
- Cytotoxic agent.
- Nematocide activity.
- Antiulcer agent.
- Anti-inflammatory drug (C5a antagonist).
Product References
- Aurantimycins, new depsipeptide antibiotics from Streptomyces aurantiacus IMET 43917: U. Graefe, et al.; J. Antibiot. 48, 119 (1995)
- Formation of membrane pores by aurantimycins A and B, new lipopeptide antibiotics from Streptomyces aurantiacus: P. Grigoriev, et al.; Bioelectrochem. Bioenerget. 36, 57 (1995)
- Pharmacological actions of a new synthetic cyclodepsipeptide, the A83586C-citropeptin hybrid, on complement C5a and G-proteins: E.-S. K. Assem, et al.; Inflamm. Res. 57, 21 (2008)
- Aurantimycin resistance genes contribute to survival of Listeria monocytogenes during life in the environment: S. Hauf, et al.; Mol. Microbiol. 111, 1009 (2019)
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