Skyrin

CHF 470.00
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BVT-0445-M0055 mgCHF 470.00
 
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Product Details
Synonyms (S)-(+)-Skyrin; 4,4′-Biemodin; Endothianin; Rhodophyscin
Product Type Chemical
Properties
Formula C30H18O10
MW 538.5
CAS 602-06-2
Source/Host Chemicals Isolated from Penicillium sp.
Purity Chemicals ≥98% (HPLC)
Appearance Dark red solid.
Solubility Soluble in DMSO.
Identity Determined by 1H-NMR, MS and optical rotation.
Declaration Manufactured by BioViotica.
InChi Key MQSXZQXHIJMNAF-UHFFFAOYSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light.
Protect from light when in solution.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
  • Mycotoxin.
  • Antibiotic (incl. MRSA).
  • Non-peptidic anti-diabetic agent (receptor-selective glucagon antagonist).
  • Inhibitor of botulinum neurotoxin serotype A (BoNTA).
  • Cytotoxic.
  • Antioxidant (free radical scavenger).
Product References
  1. A comparative study on cytotoxicities and biochemical properties of anthraquinone mycotoxins emodin and skyrin from Penicillium islandicum Sopp: K. Kawai, et al.; Toxicol. Lett. 20, 155 (1984)
  2. Effects of skyrin, a receptor-selective glucagon antagonist, in rat and human hepatocytes: J.C. Parker, et al.; Diabetes 49, 2079 (2000)
  3. Antioxidant and scavenging activity of skyrin on free radical and some reactive oxygen species: F. Vargas, et al.; Avances en Quimica 3, 7 (2008)
  4. The bioactive metabolites of the mangrove endophytic fungus Talaromyces sp. ZH-154 isolated from Kandelia candel (L.) Druce: F. Liu, et al.; Planta Med. 76, 185 (2010)
  5. Fungal bis-naphthopyrones as inhibitors of Botulinum neurotoxin serotype A: J. H. Cardellina II, e. Al.; ACS Med. Chem. Lett. 3, 387 (2012)
  6. Atropisomeric dihydroanthracenones as inhibitors of multiresistant Straphylococcus aureus: R. Bara, et al.; J. Med. Chem. 56, 3257 (2013)
  7. Antibiotically active metabolites from Talaromyces wortmannii, an endophyte of Aloe vera: R. Bara, et al.; J. Antibiot. 66, 491 (2013)
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