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BioViotica
Fridamycin E
110
CHF
CHF 110.00
In stock
BVT-0472-M0011 mgCHF 110.00
BVT-0472-M0055 mgCHF 325.00
| Product Details | |
|---|---|
| Synonyms | 9,10-Dihydro-β,1,5-trihydroxy-β-methyl-9,10-dioxo-2-anthracenebutanoic acid |
| Product Type | Chemical |
| Properties | |
| Formula |
C19H16O7 |
| MW | 356.3 |
| CAS | 116120-54-8 |
| Source/Host Chemicals | Isolated from Streptomyces parvulus. |
| Purity Chemicals | ≥98% (HPLC, NMR) |
| Appearance | Yellow to orange crystals. |
| Solubility | Soluble in DMSO. Sparingly soluble in methanol or acetone. |
| Identity | Determined by 1H-NMR and MS. |
| Declaration | Manufactured by BioViotica. |
| InChi Key | MVEDBMGRQONWSQ-LJQANCHMSA-N |
| Smiles | C[C@](O)(CC(O)=O)CC1=C(O)C2=C(C=C1)C(=O)C1=C(C=CC=C1O)C2=O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light. |
| Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. Store solutions at -20°C in the dark. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Anthraquinone derivative derived from an angucyclinone precursor.
- Antibiotic.
- Antibacterial agent.
Product References
- Fridamycine, Anthracyclin-analoge Antibiotica: P. Knicke; Ph. D. Thesis Univ. Goettingen (1984)
- Synthesis of rac- and ent-fridamycin E: K. Krohn & W. Baltus; Tetrahedron 44, 49 (1988)
- Synthetic anthracyclines from anthraquinones: R. Cambie, et al.; Austr. J. Chem. 45, 483 (1992)
- C-Aryl glycosides via tandem intramolecular benzyne-furan cycloadditions. Total synthesis of vineomycine B2 methyl ester: C.-L. Chen, et al.; JACS 128, 13696 (2006)
- A chemoenzymatic, enantioconvergent, asymmetric total synthesis of (R)-fridamycin E: B.J. Ueberbacher, et al.; Eur. J. Org. Chem. 7, 1266 (2005)
- Gephyromycin, the first bridged angucyclinone, from streptomyces griseus strain NTK 14: G. Bringmann, et al.; Phytochemistry 66, 1366 (2005)
- De novo asymmetric synthesis of fridamycin E: Q. Chen, et al.; Org. Lett. 13, 6592 (2011)
- Angucyclines from an insect-derived actinobacterium Amycolatopsis sp. HCa1 and their cytotoxic activity: Z.K. Guo, et al.; Bioorg. Med. Chem. Lett. 22, 7490 (2012)
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