Fridamycin E

CHF 110.00
In stock
BVT-0472-M0011 mgCHF 110.00
BVT-0472-M0055 mgCHF 325.00
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Product Details
Synonyms 9,10-Dihydro-β,1,5-trihydroxy-β-methyl-9,10-dioxo-2-anthracenebutanoic acid
Product Type Chemical


MW 356.3
CAS 116120-54-8
Source/Host Chemicals Isolated from Streptomyces parvulus.
Purity Chemicals ≥98% (HPLC, NMR)
Appearance Yellow to orange crystals.
Solubility Soluble in DMSO. Sparingly soluble in methanol or acetone.
Identity Determined by 1H-NMR and MS.
Declaration Manufactured by BioViotica.
Smiles C[C@](O)(CC(O)=O)CC1=C(O)C2=C(C=C1)C(=O)C1=C(C=CC=C1O)C2=O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Store solutions at -20°C in the dark.
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
  • Anthraquinone derivative derived from an angucyclinone precursor.
  • Antibiotic.
  • Antibacterial agent.
Product References
  1. Fridamycine, Anthracyclin-analoge Antibiotica: P. Knicke; Ph. D. Thesis Univ. Goettingen (1984)
  2. Synthesis of rac- and ent-fridamycin E: K. Krohn & W. Baltus; Tetrahedron 44, 49 (1988)
  3. Synthetic anthracyclines from anthraquinones: R. Cambie, et al.; Austr. J. Chem. 45, 483 (1992)
  4. C-Aryl glycosides via tandem intramolecular benzyne-furan cycloadditions. Total synthesis of vineomycine B2 methyl ester: C.-L. Chen, et al.; JACS 128, 13696 (2006)
  5. A chemoenzymatic, enantioconvergent, asymmetric total synthesis of (R)-fridamycin E: B.J. Ueberbacher, et al.; Eur. J. Org. Chem. 7, 1266 (2005)
  6. Gephyromycin, the first bridged angucyclinone, from streptomyces griseus strain NTK 14: G. Bringmann, et al.; Phytochemistry 66, 1366 (2005)
  7. De novo asymmetric synthesis of fridamycin E: Q. Chen, et al.; Org. Lett. 13, 6592 (2011)
  8. Angucyclines from an insect-derived actinobacterium Amycolatopsis sp. HCa1 and their cytotoxic activity: Z.K. Guo, et al.; Bioorg. Med. Chem. Lett. 22, 7490 (2012)
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