BioViotica

Fridamycin B

CHF 110.00
In stock
BVT-0470-M0011 mgCHF 110.00
BVT-0470-M0055 mgCHF 325.00
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Product Details
Synonyms 3'-Epimer of Fridamycin A
Product Type Chemical
Properties
Formula

C25H26O10

MW 486.5
Source/Host Chemicals Isolated from Streptomyces parvulus.
Purity Chemicals ≥98% (HPLC, NMR)
Appearance Yellow to brown solid.
Solubility Soluble in DMSO. Sparingly soluble in methanol or acetone.
Identity Determined by 1H-NMR.
Declaration Manufactured by BioViotica.
InChi Key LKLNNJGYAYDANM-XLTBZDRQSA-N
Smiles [H][C@@]1(C[C@H](O)[C@H](O)[C@@H](C)O1)C1=C(O)C2=C(C=C1)C(=O)C1=C(C=CC(C[C@@](C)(O)CC(O)=O)=C1O)C2=O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Store solutions at -20°C in the dark.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description
  • C-glycosidic angucyclinone derivative.
  • Antibiotic.
  • Antitumor agent.
  • Antibacterial agent.
  • Isomer of fridamycin A (Prod. No. BVT-0469).
Product References
  1. The structure of vineomycin B2: N. Imamura, et al.; J. Antibiot. 34, 1517 (1981)
  2. Fridamycine, Anthracyclin-analoge Antibiotica: P. Knicke; Ph. D. Thesis Univ. Goettingen (1984)
  3. Angucycline group antibiotics: J. Rohr & R. Thiericke; Nat. Prod. Rep. 9, 103 (1992)
  4. Synthetic anthracyclines from anthraquinones: R. Cambie, et al.; Austr. J. Chem. 45, 483 (1992)
  5. C-Aryl glycosides via tandem intramolecular benzyne-furan cycloadditions. Total synthesis of vineomycine B2 methyl ester: C.-L. Chen, et al.; JACS 128, 13696 (2006)
  6. Convergent de novo synthesis of vineomycinione B2 methyl ester: Q. Chen, et al.; Chem. Comm. 49, 6806 (2013)
  7. Total Synthesis of vineomycin B2: S. Kusumi, et al.; JACS 135, 15909 (2013)
  8. Angucycline antibiotics and its derivatives from marine-derived actinomycete streptomyces sp. A6H: Z. Hu, et al.; Nat. Prod. Res. 30, 2551 (2016)
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