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BioViotica
Violacein
470
CHF
CHF 470.00
In stock
BVT-0473-M0011 mgCHF 470.00
| Product Details | |
|---|---|
| Synonyms | Anorosin |
| Product Type | Chemical |
| Properties | |
| Formula |
C20H13N3O3 |
| MW | 343.3 |
| CAS | 548-54-9 |
| Source/Host Chemicals | Isolated from Chromobacterium violaceum. |
| Purity Chemicals | ≥97% (HPLC, NMR) |
| Appearance | Dark purple to black solid. |
| Solubility | Soluble in DMSO. Partially soluble in methanol. Insoluble in water and usual organic solvents. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by BioViotica. |
| InChi Key | XAPNKXIRQFHCHN-QGOAFFKASA-N |
| Smiles | OC1=CC2=C(NC=C2C2=C\C(C(=O)N2)=C2/C(=O)NC3=C2C=CC=C3)C=C1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light. |
| Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Antibacterial, antifungal and antiprotozoal agent.
- Quorum sensing metabolite.
- Antitumor compound.
- Protective against UV-C irradiation.
- Possesses immunomodulatory, analgesic and antipyretic activity.
- Antiulcerogenic and antiviral agent.
- Indole-derived purple-colored pigment (free of deoxyviolacein).
Product References
- The synthesis of violacein and related compounds: J.A. Ballantine, et al.; J. Chem. Soc. [London] 1960, 2292 (1960)
- Evaluation of the antiulcerogenic activity of violacein and its modulation by the inclusion complexation with beta-cyclodextrin: N. Duran, et al.; Can. J. Physiol. Pharmacol. 81, 387 (2003)
- Cytotoxicity and potential antiviral evaluation of violacein produced by Chromobacterium violaceum: C.R. Andrighetti-Froehner, et al.; Mem. Inst. Oswaldo Cruz. 98, 843 (2003)
- Violacein: properties and biological activities: N. Duran, et al.; Biotechn. Appl. Biochem. 48, 127 (2007)
- The protective effects of the violacein pigment against UV-C irradiation in Chromobacterium violaceum: A.N. Abboud & A. Arment; Ohio J. Sci. 111, 28 (2013)
- Violacein: properties and production of a versatile bacterial pigment: S.Y. Choi, et al.; Biomed Res. Int. 2015, 1 (2015)
- Violacein treatment modulates acute and chronic inflammation through the suppression of cytokine production and induction of regulatory T cells: L. Verinaud, et al.; PLoS One 10, e0125409 (2015)
- Violacein induces cell death by triggering mitochondrial membrane hyperpolarization in vitro: A.M. Leal, et al.; Microbiol. 15, 1 (2015)
- Antifungal activity of violacein purified from a novel strain of Chromobacterium sp. NIIST (MTCC 5522): A. Sasidharan, et al.; J. Microbiol. [Seoul] 53, 694 (2015)
- Violacein, an indole-derived purple-colored natural pigment produced by Janthinobacterium lividum, inhibits the growth of head and neck carcinoma cell lines both in vitro and in vivo: L. Masuelli, et al.; Tumor Biol. 37, 3705 (2016)
- Violacein induces apoptosis in human breast cancer cells through up regulation of BAX, p53 and down regulation of MDM2: A.A. Alshatwi, et al.; Exp. Toxicol. Pathol. 68, 89 (2016)
- Advances in Chromobacterium violaceum and properties of violacein-Its main secondary metabolite: A review: N. Duran, et al.; Biotechnol. Adv. 34, 1030 (2016)
- Violacein antimicrobial activity on Staphylococcus epidermidis and synergistic effect on commercially available antibiotics: H.V. Dodou, et al.; J. Appl. Microbiol. 123, 853 (2017)
- Violacein and bacterial predation: promising alternatives for priority multidrug resistant human pathogens: S.Y. Choi, et al.; Future Microbiol. 12, 835 (2017)
- Antibacterial mode of action of violacein from Chromobacterium violaceum UTM5 against Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA): C.A. Aruldass, et al.; Environ. Sci. Pollut. Res. 25, 5164 (2017)
- Action and function of Chromobacterium violaceum in health and disease: Violacein as a promising metabolite to counteract gastroenterological diseases: G. Justo & N. Duran; Best. Pract. Res. Clin. Gastroenterol. 31, 649 (2017)
- Antibacterial mode of action of violacein from Chromobacterium violaceum UTM5 against Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA): C.A. Aruldass, et al.; Environ. Sci. Pollut. R. 25, 5164 (2018)
- Prodigiosin, violacein, and volatile organic compounds produced by widespread cutaneous bacteria of amphibians can inhibit two batrachochytrium fungal pathogens: D.C. Woodhams, et al.; Microb. Ecol. 75, 1049 (2018)
- Impact of violacein from Chromobacterium violaceum on the mammalian gut microbiome: H. Pauer, et al.; PLoS One 13, e0203748/1 (2018)
- Violacein Targets the Cytoplasmic Membrane of Bacteria: A. Cauz, et al.; ACS Infect. Dis. 5, 539 (2019)
- Violacein antimicrobial activity on Staphylococcus epidermidis biofilm: H.V. Dodou, et al.; Nat. Prod. Res. Online (2019)
- The bacterial product violacein exerts an immunostimulatory effect via TLR8: F. Venegas, et al.; Sci. Rep. 9, 1 (2019)
- Antichagasic effect of violacein from Chromobacterium violaceum: J.A. Canuto, et al.; J. Appl. Microbiol. 127, 1373 (2019)
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