Cancer

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  1. MLN4924 [NAE Inhibitor]
    CAS  905579-51-3
    AG-CR1-3703
    AG-CR1-3703-M0055 mg
    CHF 120.00
    AG-CR1-3703-M02525 mg
    CHF 480.00
    MLN4924 [NAE Inhibitor]
  2. MLN4924 [NAE Inhibitor] Solution
    CAS  905579-51-3
    AG-CS1-0103
    AG-CS1-0103-M0011 mg
    CHF 250.00
    MLN4924 [NAE Inhibitor] Solution
  3. Nedd4 E3 Ligase TR-FRET Kit
    SBB-KF0056
    SBB-KF0056-KI011 Kit
    CHF 1'250.00
    % Signal to Background of Continuous Real-Time TR-FRET Parkin titration (autoubiquitination): Serial dilutions of Parkin W403A from 50nM to 3.125nM and 300nM wt Parkin were mixed with UBA1, UBE2D3 and trf-Ub (pS65) mix. Reactions were initiated wit
  4. NEDD8 (human) (rec.) (Rhodamine 110)
    SBB-PS0003
    SBB-PS0003-C05050 µg
    CHF 434.00
    Signal to Background: The signal to background ratio was determined by 100% hydrolysis of 800nM, 400nM, 200nM, 100nM, 50nM NEDD8-Rhodamine 110 to liberate the quenched conjugate. Assay Buffer: 50mM HEPES pH7.5, 1mM TCEP, 0.1mg/ml BSA.
  5. NEDD8-AMC (human) (rec.) (untagged)
    SBB-PS0044
    SBB-PS0044-C05050 µg
    CHF 360.00
    NEDD8-AMC (human) (rec.) (untagged)
  6. NEDP1 [SENP8] (human) (rec.) (His)
    SBB-DE0025
    SBB-DE0025-C05050 µg
    CHF 243.00
    Michaelis–Menten Kinetics: NEDD8 Rhodamine 110 serially diluted from 1.6 to 0.0125µM was digested with 30pM NEDP1 over time. The assay was carried out in a reaction buffer of 50mM HEPES pH 7.5, 1mM TCEP, 0.1 mg/ml BSA, at 25°C. Initial velocities a
  7. p53 (polyubiquitinated) (human) (rec.) (His)
    SBB-US0012
    SBB-US0012-C02020 µg
    CHF 639.00
    Ubiquitinated-p53 Western Blot: From left to right: Control His6-p53 (50ng), ubiquitinated-p53 (50ng and 100ng) and ubiquitinated-p53 digested with USP7 (50ng).
  8. Parkin (E3 Ligase) (human) (rec.) (His)
    SBB-CE0055
    SBB-CE0055-C05050 µg
    CHF 557.00
    Parkin (E3 Ligase) (human) (rec.) (His)
  9. Parkin E3 Ligase TR-FRET Kit
    SBB-KF0036
    SBB-KF0036-KI011 Kit
    CHF 1'250.00
    Parkin E3 Ligase TR-FRET Kit
  10. Parthenolide
    CAS  20554-84-1
    AG-CN2-0455
    AG-CN2-0455-M01010 mg
    CHF 35.00
    AG-CN2-0455-M05050 mg
    CHF 80.00
    AG-CN2-0455-M250250 mg
    CHF 240.00
    Parthenolide

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