Hoechst 34580

CHF 68.00
In stock
CDX-B0094-M0055 mgCHF 68.00
CDX-B0094-M05050 mgCHF 407.00
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Product Details
Synonyms HOE 34580 . 3HCl; N,N-Dimethyl-4-[5-(4-methyl-1-piperazinyl)[2,5′-bi-1H-benzimidazol]-2′-yl]benzenamine trihydrochloride
Product Type Chemical

C27H29N7 . 3HCl

MW 561.0
CAS 911004-45-0 | 23555-00-2 (free base)
Source/Host Chemicals Synthetic.
Purity Chemicals ≥98% (HPLC)
Appearance Dark yellow solid.
Solubility Soluble in DMSO, DMF or water (1mg/ml).
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Smiles CCCCCCCC(=O)OC1=CC2=C(C=C1)C=C(C1=NC3=C(O1)C=CC=C3)C(=O)O2
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at +4°C.
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF

The Hoechst stains are a family of fluorescent stains for labeling DNA in fluorescence microscopy. The blue fluorescent Hoechst dye is a cell permeable nucleic acid stain that has multiple applications, including sensitive detection of DNA in the presence of RNA in agarose gels, automated DNA determination, sensitive determination of cell number and chromosome sorting. Useful vital stain for the flow cytometric recognition of DNA damage and other viability measurements by monitoring the emission spectral shifts of the dyes. Because this fluorescent stain labels DNA, it can also be used to visualize nuclei and mitochondria. Hoechst 34580 can be excited by violet laser at 405 nm, and emit blue/cyan fluorescence light around an emission maximum at ~440 nm. It is cell-permeable and an excellent tool for flow cytometry studies.

Product References

(1) S.A. Latt & G. Stetten; J. Histochem. Cytochem. 24, 24 (1976) | (2) D.P. Kelly, et al.; Aus. J. Chem. 47, 1751 (1994) | (3) W.G. Telford, et al.; Cytometry A. 54, 48 (2003) | (4) D.A. Evans & S. Neidle; J. Med. Chem. 49, 4232 (2006) | (5) W. Lei, et al.; ChemPhysChem 12, 2933 (2011)

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