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5-FAM
48
CHF
CHF 48.00
In stock
CDX-C0014-M02525 mgCHF 48.00
CDX-C0014-M100100 mgCHF 143.00
CDX-C0014-G0011 gCHF 1'142.00
| Product Details | |
|---|---|
| Synonyms | 5-Carboxyfluorescein |
| Product Type | Chemical |
| Properties | |
| Formula | C21H12O7 |
| MW | 376.32 |
| CAS | 76823-03-5 |
| Source/Host Chemicals | Synthetic. |
| Purity Chemicals | ≥99% (HPLC) |
| Appearance | Yellow-orange solid. |
| Solubility | Soluble in water, DMSO or DMF. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | VPMWLNJETPKSSC-UHFFFAOYSA-N |
| Smiles | OC(=O)C1=CC=C(C(=C1)C(O)=O)C1=C2C=CC(=O)C=C2OC2=CC(O)=CC=C12 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
The amine-reactive fluorescein derivatives are probably the most common fluorescent derivatization reagents for covalently labeling proteins. Carboxyfluorescein is better retained in cells than is fluorescein, its pKa of ~6.5 is lower than the cytosolic pH of most cells (pH ~6.8-7.4). Carboxyfluorescein is commonly employed as a polar tracer.
Product References
(1) R. Fischer et al., Bioconjugate Chem. 14, 653 (2003) | (2) E. Ralston et al., Biochim. Biophys. Acta, Biomembranes 649(1), 133 (1981)
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