3-Carboxy-6,8-difluoro-7-hydroxycoumarin

CHF 140.00
In stock
CDX-C0036-M02525 mgCHF 140.00
CDX-C0036-M100100 mgCHF 421.00
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Product Details
Synonyms NHS Pacific Blue succinimidyl ester; 2,5-Dioxopyrrolidin-1-yl 6,8-difluoro-7-hydroxy-2-oxo-2H-chromene-3-carboxylate
Product Type Chemical
Properties
Formula

C14H7F2NO7

MW 339.2
CAS 215868-33-0
Source/Host Chemicals Synthetic.
Purity Chemicals ≥98% (HPLC)
Appearance Yellow powder.
Solubility Soluble in chloroform.
Identity Determined by NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key NZYXABPVYJRICY-UHFFFAOYSA-N
Smiles OC1=C(F)C2=C(C=C1F)C=C(C(=O)ON1C(=O)CCC1=O)C(=O)O2
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF

This amine-reactive reagent can be used to create blue-fluorescent bioconjugates with excitation/emission maxima ~410/455 nm that are excitable by the 405 nm spectral line of the blue diode (violet) laser. Used in highly sensitive analyses of amines, amino acids and dipeptides. Amine-reactive reagents react with non-protonated aliphatic amine groups, including the amine terminus of proteins and the є-amino group of lysines.

Product References

(1) B. Abrams, et al.; Anal. Biochem. 386, 262 (2009) | (2) T.N. Chiesl, et al.; Anal. Chem. 81, 2537 (2009) | (3) J.D. Cohen, et al.; Biochem. 50, 8221 (2011) | (4) A.M. Stockton, et al.; Dyes & Pigments 96, 148 (2013)

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