Chemodex

Cefpodoxime

As low as CHF 48.00

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CDX-C0361-M02525 mgCHF 48.00

CDX-C0361-M100100 mgCHF 156.00

Specifications / Handling

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Product Details
Synonyms	R 3763; (6R,7R)-7-{2-(2-Amino-4-thiazolyl)-2-[(Z)-methoxy-imino]acetamido}-3-(methoxymethyl)-3-cephem-4-carboxylate
Product Type	Chemical
Properties
Formula	C₁₅H₁₇N₅O₆S₂
MW	427.46
CAS	80210-62-4
Source/Host Chemicals	Synthetic.
Purity Chemicals	≥98%
Appearance	White to off-white powder.
Solubility	Soluble in DMSO, ethanol or methanol (all 10mg/ml).
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by Chemodex.
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	WYUSVOMTXWRGEK-LMCFTXQDSA-N
Smiles	O=C1[C@@H](NC(/C(C2=CSC(N)=N2)=N/OC)=O)[C@]3([H])N1C(C(O)=O)=C(COC)CS3
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
Product Specification Sheet
Datasheet	Download PDF

Scientific Background Information

Product Description

Cefpodoxime is a metabolite of cefpodoxime proxetil, an oral third generation cephalosporin antibiotic. It is active against most Gram positive and Gram negative bacteria (MIC90 ranges from 0.015-8 µg/ml). It is commonly used to treat acute otitis media, pharyngitis, and sinusitis. Cefpodoxime inhibits cell wall synthesis by inhibiting the final transpeptidation step of peptidoglycan synthesis in cell walls.

Product-specific References

(1) K. Fujimoto, et al.; J. Antibiot. 40, 370 (1987) | (2) Y. Utsui, et al.; Antimicrob. Agents Chemother. 31, 1085 (1987) | (3) P. Angehrn, et al.; Antimicrob. Agents Chemother. 36, 2825 (1992) | (4) J.E. Frampton, et al.; Drugs 44, 889 (1992) (Review) | (5) E.C. Chocas, et al.; Ann. Pharmacother. 27, 1369 (1993) (Review)

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