Cefpodoxime

Specifications / Handling

More Information
Product Details
Synonyms	R 3763; (6R,7R)-7-{2-(2-Amino-4-thiazolyl)-2-[(Z)-methoxy-imino]acetamido}-3-(methoxymethyl)-3-cephem-4-carboxylate
Product Type	Chemical
Properties
Formula	C₁₅H₁₇N₅O₆S₂
MW	427.46
CAS	80210-62-4
Source/Host Chemicals	Synthetic.
Purity Chemicals	≥98%
Appearance	White to off-white powder.
Solubility	Soluble in DMSO, ethanol or methanol (all 10mg/ml).
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by Chemodex.
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	WYUSVOMTXWRGEK-LMCFTXQDSA-N
Smiles	O=C1[C@@H](NC(/C(C2=CSC(N)=N2)=N/OC)=O)[C@]3([H])N1C(C(O)=O)=C(COC)CS3
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

Cefpodoxime is a metabolite of cefpodoxime proxetil, an oral third generation cephalosporin antibiotic. It is active against most Gram positive and Gram negative bacteria (MIC90 ranges from 0.015-8 µg/ml). It is commonly used to treat acute otitis media, pharyngitis, and sinusitis. Cefpodoxime inhibits cell wall synthesis by inhibiting the final transpeptidation step of peptidoglycan synthesis in cell walls.

Product References

(1) K. Fujimoto, et al.; J. Antibiot. 40, 370 (1987) | (2) Y. Utsui, et al.; Antimicrob. Agents Chemother. 31, 1085 (1987) | (3) P. Angehrn, et al.; Antimicrob. Agents Chemother. 36, 2825 (1992) | (4) J.E. Frampton, et al.; Drugs 44, 889 (1992) (Review) | (5) E.C. Chocas, et al.; Ann. Pharmacother. 27, 1369 (1993) (Review)

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