Ohira-Bestmann Reagent

CHF 191.00
In stock
CDX-D0501-G0011 gCHF 191.00
CDX-D0501-G0055 gCHF 767.00
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Product Details
Synonyms Dimethyl (1-diazo-2-oxopropyl)phosphonate; Ohira-Bestmann phosphonate; α-Azido-α-(dimethyl phosphono)acetone
Product Type Chemical
Properties
Formula C5H9N2O4P
MW 192.11
CAS 90965-06-3
Source/Host Chemicals Synthetic.
Purity Chemicals ≥96% (HPLC)
Appearance Yellow liquid.
Solubility Soluble in acetonitrile.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key SQHSJJGGWYIFCD-UHFFFAOYSA-N
Smiles COP(=O)(OC)C(=[N+]=[N-])C(C)=O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF

Used in the Seyferth-Gilbert homologation which is a chemical reaction of an aryl ketone or aldehyde with dimethyl- or diazomethyl-phosphonate and potassium tert-butoxide to give substituted alkynes.

Product References

(1) P. Callant et al.; Synthetic Communications 14(2), 155-61(1984) | (2) S. Ohira; Synthetic Communications 19(3-4), 561-4 (1989) | (3) S. Kasteren et al.; Nature 446(7139), 1105-1109 (2007) | (4) G.J. Roth et al.; Synthesis (1), 59-62 (2004)

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