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Chemodex
N-(3-Hydroxyoctanoyl)-L-homoserine lactone
Product Details | |
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Synonyms | OH-C8-HSL; 3-Hydroxy-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-octanamide |
Product Type | Chemical |
Properties | |
Formula | C12H21NO4 |
MW | 243.30 |
CAS | 192883-14-0 |
Source/Host Chemicals | Synthetic. |
Purity Chemicals | ≥98% (HPLC) |
Appearance | White to off-white powder. |
Solubility | Soluble in DMSO, DMF or acetonitrile. |
Identity | Determined by 1H-NMR. |
Declaration | Manufactured by Chemodex. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | XCZVBYOXRSFQBH-AXDSSHIGSA-N |
Smiles | O=C1[C@@H](NC(CC(O)CCCCC)=O)CCO1 |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice | Protect from light and moisture. |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS | Inquire |
Product Specification Sheet | |
Datasheet | Download PDF |
3-Hydroxy-octanoyl-L-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms.
(1) L.R. Flodgaard, et al.; Appl. Environ. Microbiol. 71, 2113 (2005) | (2) P. Lumjiaktase, et al.; Microbiol. 152, 3651 (2006) | (3) B.A. Duerkop, et al.; J. Bacteriol. 190, 5137 (2008) | (4) A.M. Gamage, et al.; Microbiol. 157, 1176 (2011) | (5) K.G. Chan, et al.; BMC Microbiol. 11, 1 (2011)