Chemodex

NBD-X SE

CHF 204.00
In stock
CDX-N0045-M02525 mgCHF 204.00
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Product Details
Synonyms NBD-X succinimidyl ester; NBD-C6 SE; 6-(7-Nitrobenzofurazan-4-ylamino)hexanoic acid NHS ester
Product Type Chemical
Properties
Formula

C16H17N5O7

MW 391.33
CAS 145195-58-0
Source/Host Chemicals Synthetic.
Purity Chemicals ≥98% (HPLC)
Appearance Orange powder.
Solubility Soluble in DMSO or DMF.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key ULIVORQJLJKPHQ-UHFFFAOYSA-N
Smiles O=C(ON1C(CCC1=O)=O)CCCCCNC2=CC=C([N+]([O-])=O)C3=NON=C32
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
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Product Specification Sheet
Datasheet Download PDF
Description

NBD-X, SE is an excellent amino-reactive building block that can be used to prepare peptide conjugates and other bioconjugates/biopolymers. It has much higher conjugation efficiency than NBD-Cl and NBD-F. This amine-reactive NBD derivative, containing a convenient succinimidyl ester, can be used to develop environmentally sensitive bioconjugates. NBD is a functional analog of the dinitrophenyl hapten, and its fluorescence is quenched upon binding to anti-dinitrophenyl (anti-DNP) antibodies. The X-spacer separates the fluorescent dye from the protein allowing greater sensitivity and reduced perturbation effects on protein labeling. Spectral properties: lamdaEx=460; lambdaEm=540.

Product References

(1) C. Sherrill, et al.; Biochemistry 34, 3553 (1995) | (2) B.K. Nunnally, et al.; Anal. Chem. 69, 2392 (1997) | (3) J.T. Elliott & G.D. Prestwich; Bioconjug. Chem. 11, 832 (2000) | (4) S. Ozaki, et al.; PNAS 97, 11286 (2000) | (5) A. Karlstrom, et al.; Anal. Biochem. 295, 22 (2001) | (6) F. Eisele, et al.; Chem. Eur. J. 8, 3362 (2002) | (7) L. Silva, et al.; J. Photochem. Photobiol. B 72, 17 (2003) | (8) J.M. Bergen, et al.; Bioconjug. Chem. 19, 377 (2008)

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