CD272 [BTLA] (human):Fc (human) (rec.)

CHF 420.00
In stock
CHI-HF-210CD272-C100100 µgCHF 420.00
More Information
Product Details
Synonyms BTLA; B- and T-lymphocyte attenuator
Product Type Protein
Properties
Source/Host CHO cells
Sequence

The extracellular domain of human CD272 (aa 31-157) is fused to the N-terminus of the Fc region of human IgG1.

Crossreactivity Human
Biological Activity

Measured in a competitive binding assay.

Purity ≥98% (SDS-PAGE)
Endotoxin Content <0.001EU/μg protein (LAL test; Lonza).
Reconstitution Reconstitute with 100 µl sterile water.
Add 1X PBS to the desired protein concentration.
Formulation Lyophilized from 0.2μm-filtered solution in PBS.
Protein Negative Control

Fc (human) IgG1 Control (rec.)

Other Product Data

NCBI reference NP_861445.3: CD272 (human)

Declaration Manufactured by Chimerigen.
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Avoid freeze/thaw cycles.
Centrifuge lyophilized vial before opening and reconstitution.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

BTLA is a type I transmembrane glycoprotein of the CD28 family of T cell costimulatory molecules. BTLA functions as a coinhibitor on activated T cells and on B cells and dendritic cells. The extracellular domain (ECD) of this Ig superfamily protein contains one V-type Ig-like domain, which interacts with HVEM.

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