CD272 [BTLA] (human):Fc (mouse) (recombinant protein)

Specifications / Handling

More Information
Product Details
Synonyms	BTLA; B- and T-lymphocyte attenuator
Product Type	Protein
Properties
Source/Host	CHO cells
Sequence	The extracellular domain of human CD272 (aa 31-157) is fused to the N-terminus of the Fc region of mouse IgG2a.
Crossreactivity	Human
Biological Activity	Measured in a competitive binding assay.
Purity	≥98% (SDS-PAGE)
Endotoxin Content	<0.06EU/μg protein (LAL test; Lonza).
Reconstitution	Reconstitute with 100 µl sterile water. Add 1X PBS to the desired protein concentration.
Formulation	Lyophilized from 0.2μm-filtered solution in PBS.
Protein Negative Control	Fc (mouse) IgG2a Control (rec.)
Other Product Data	NCBI reference NP_861445.3: CD272 (human)
Declaration	Manufactured by Chimerigen.
Shipping and Handling
Shipping	BLUE ICE
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution.
Use/Stability	Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

BTLA is a type I transmembrane glycoprotein of the CD28 family of T cell costimulatory molecules. BTLA functions as a coinhibitor on activated T cells and on B cells and dendritic cells. The extracellular domain (ECD) of this Ig superfamily protein contains one V-type Ig-like domain, which interacts with HVEM.

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CD272 [BTLA] (human):Fc (mouse) (rec.)