CD252 [OX40L] (human):Fc (mouse) (recombinant protein)

Specifications / Handling

More Information
Product Details
Synonyms	TNFSF4
Product Type	Protein
Properties
Source/Host	HEK 293 cells
Sequence	The extracellular domain of human CD252 (aa 51-183) is fused to the N-terminus of the Fc region of mouse IgG2a.
Crossreactivity	Human Mouse
Biological Activity	Measured by its binding ability in a functional ELISA.
MW	~55kDa (SDS-PAGE)
Purity	≥98% (SDS-PAGE)
Endotoxin Content	<5EU/mg purified protein (LAL test; Lonza).
Reconstitution	Reconstitute with 100μl sterile water. Add 1X PBS to the desired protein concentration.
Formulation	Lyophilized from 0.2μm-filtered solution in PBS.
Protein Negative Control	Fc (mouse) IgG2a Control (rec.)
Other Product Data	NCBI reference NP_003317: CD252 (human)
Shipping and Handling
Shipping	BLUE ICE
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution.
Use/Stability	Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

OX40L [CD252; TNFSF4] is a membrane-expressed cytokine that belongs to the TNF ligand family. It acts as costimulator through interaction with its ligand OX40 on T cells, stimulating T cell activation, proliferation and cytokine production. OX40L is expressed on antigen presenting cells including B cells, dendritic cells, mast cells and endothelium.

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CD252 [OX40L] (human):Fc (mouse) (rec.)