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RevMab
anti-TIM3 (Hepatitis A Virus Cellular Receptor 2), Rabbit Monoclonal (RM448)
459
CHF
CHF 459.00
In stock
REV-31-1340-00-R100100 µlCHF 459.00
Figure 1: Immunohistochemical staining of formalin-fixed and paraffin-embedded human lung cancer tissue section using anti-TIM3 rabbit monoclonal antibody (Clone RM448) at a 1:200 dilution.
| Product Details | |
|---|---|
| Synonyms | T-cell Immunoglobulin and Mucin Domain-containing Protein 3; Hepatitis A Virus Cellular Receptor 2 |
| Product Type | Recombinant Antibody |
| Properties | |
| Clone | RM448 |
| Isotype | Rabbit IgG |
| Source/Host | Rabbit |
| Immunogen/Antigen | Recombinant human TIM3 (Hepatitis A virus cellular receptor 2) protein. |
| Application |
Immunohistochemistry: 1:100 - 1:200 |
| Crossreactivity | Human |
| Specificity |
This antibody reacts to human TIM3 (Hepatitis A virus cellular receptor 2). |
| Purity | Protein A purified. |
| Purity Detail | Protein A affinity purified from an animal origin-free culture supernatant. |
| Formulation | Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Accession Number | P0C0S5 |
| Declaration | Manufactured by RevMab Biosciences. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
T cell Immunoglobulin and Mucin Domain-containing Molecule-3 (TIM-3) is present on T-helper type 1 lymphocytes and other immune cells including dendritic cells and natural killer cells. TIM-3 is overexpressed in CD4+ tumor-infiltrating lymphocytes, including those with non-small cell lung cancer associated with poor prognoses. The TIM gene family has an important role in the regulation of autoimmunity and allergies. TIM-3 has recently emerged as a potential target for cancer immunotherapy.
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