RevMab

anti-5-Formylcytosines (5-fC), Rabbit Monoclonal (RM477)

CHF 600.00
In stock
REV-31-1369-00-C05050 µgCHF 600.00
More Information
Product Details
Synonyms 5-fC
Product Type Recombinant Antibody
Properties
Clone RM477
Isotype Rabbit IgG
Source/Host Rabbit
Immunogen/Antigen KLH-conjugated 5-Formylcytosine.
Application

DotBlot: 0.5 µg/ml -2 µg/ml
ELISA: 0.5 µg/ml -2 µg/ml

Crossreactivity All
Specificity

RM477 reacts to 5-Formylcytosine (5-fC) in DNA. No cross-reactivity with non-modified cytosine and other modified cytosines in DNA.

Purity Protein A purified.
Purity Detail Protein A affinity purified from an animal origin-free culture supernatant.
Concentration 1 mg/ml
Formulation Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Isotype Negative Control

Rabbit IgG

Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Accession Number N/A
Declaration Manufactured by RevMab Biosciences.
Shipping and Handling
Shipping BLUE ICE
Long Term Storage -20°C
Handling Advice Avoid freeze/thaw cycles.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF
Description

5-Formylcytosine (5fC) is a pyrimidine nitrogen base derived from cytosine and a recently discovered modification of DNA. Just as 5-hydroxymethylcytosine (5-hmC) is generated when the Tet family of cytosine oxygenase enzymes converts 5-methylcytosine (5-mC), it has been shown that continued activity of the Tet proteins on hydroxymethylcytosine will generate 5-formylcytosine (5-fC) and 5-carboxylcytosine. It is believed that this conversion process may represent a pathway of DNA demethylation.

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