BMS-2

CHF 299.00
In stock
SYN-1022-M0011 mgCHF 299.00
SYN-1022-M0055 mgCHF 898.00
SYN-1022-M01010 mgCHF 1'496.00
 
More Information
Product Details
Synonyms BMS2
Product Type Chemical
Properties
Formula C25H16F2N4O3
MW 458.4
CAS 888719-03-7
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO or ethanol. Slightly soluble (<1mg/ml) in water.
Declaration Manufactured by SynKinase.
Other Product Data Target: MET | Kinase Group: RTK | Substrate: Tyrosine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key OBSFXHDOLBYWRJ-UHFFFAOYSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
BMS-2 is a potent MET kinase inhibitor with an IC(50) value of 1.8nM. It also possesses potent inhibitory activity against Flt-3 and VEGFR-2 kinases, IC(50) values of 4nM and 27nM respectively.
Product References
  1. Discovery of pyrrolopyridine-pyridone based inhibitors of Met kinase: synthesis, X-ray crystallographic analysis, and biological activities: K.S. Kim, et al.; J. Med. Chem. 51, 5330 (2008)
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