SYN-1022-M0011 mgCHF 299.00
SYN-1022-M0055 mgCHF 898.00
SYN-1022-M01010 mgCHF 1'496.00
|Solubility||Soluble in DMSO or ethanol. Slightly soluble (<1mg/ml) in water.|
|Declaration||Manufactured by SynKinase.|
|Other Product Data||
Target: MET | Kinase Group: RTK | Substrate: Tyrosine
Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
|Shipping and Handling|
|Short Term Storage||+4°C|
|Long Term Storage||-20°C|
|Use/Stability||Stable for at least 2 years after receipt when stored at -20°C.|
|Product Specification Sheet|
BMS-2 is a potent MET kinase inhibitor with an IC(50) value of 1.8nM. It also possesses potent inhibitory activity against Flt-3 and VEGFR-2 kinases, IC(50) values of 4nM and 27nM respectively.
- Discovery of pyrrolopyridine-pyridone based inhibitors of Met kinase: synthesis, X-ray crystallographic analysis, and biological activities: K.S. Kim, et al.; J. Med. Chem. 51, 5330 (2008)