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SynKinase
BMS-2
355
CHF
CHF 355.00
In stock
SYN-1022-M0011 mgCHF 355.00
SYN-1022-M0055 mgCHF 1'064.00
SYN-1022-M01010 mgINQ
| Product Details | |
|---|---|
| Synonyms | BMS2 |
| Product Type | Chemical |
| Properties | |
| Formula | C25H16F2N4O3 |
| MW | 458.4 |
| CAS | 888719-03-7 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO or ethanol. Slightly soluble (<1mg/ml) in water. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: MET | Kinase Group: RTK | Substrate: Tyrosine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | OBSFXHDOLBYWRJ-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
BMS-2 is a potent MET kinase inhibitor with an IC(50) value of 1.8nM. It also possesses potent inhibitory activity against Flt-3 and VEGFR-2 kinases, IC(50) values of 4nM and 27nM respectively.
Product References
- Discovery of pyrrolopyridine-pyridone based inhibitors of Met kinase: synthesis, X-ray crystallographic analysis, and biological activities: K.S. Kim, et al.; J. Med. Chem. 51, 5330 (2008)
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