CHF 85.00
In stock
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More Information
Product Details
Synonyms CYC-116
Product Type Chemical
Formula C18H20N6OS
MW 368.5
CAS 693228-63-6
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO or ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: Aurora A | Kinase Group: Other | Substrate: Serine-Threonine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
CYC116 is an orally active small molecule multi-kinase inhibitor with anti-neoplastic activity. CYC116 inhibits Aurora kinases A/B and vascular endothelial growth factor receptor 2 (VEGFR2), resulting in disruption of the cell cycle, rapid cell death, and the inhibition of angiogenesis.
Product References
  1. Discovery and development of aurora kinase inhibitors as anticancer agents: J.R. Pollard & M.J. Mortimore; J. Med. Chem. 52, 2629 (2009)
  2. Selectivity data: assessment, predictions, concordance, and implications: C. Gao, et al.; J. Med. Chem. 56, 6991 (2013)
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