E7080

CHF 108.00
In stock
SYN-1038-M0011 mgCHF 108.00
SYN-1038-M0055 mgCHF 168.00
SYN-1038-M01010 mgCHF 263.00
SYN-1038-M05050 mgCHF 886.00
SYN-1038-M100100 mgCHF 1'412.00
 
More Information
Product Details
Synonyms E-7080; Lenvatinib
Product Type Chemical
Properties
Formula C21H19ClN4O4
MW 426.9
CAS 417716-92-8
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO or ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: FGFR - VEGFR - SCF | Kinase Group: RTK | Substrate: Tyrosine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key WOSKHXYHFSIKNG-UHFFFAOYSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
E7080 is an orally active inhibitor of multiple receptor tyrosine kinases including VEGF, FGF and SCF receptors. It is most potent against VEGFR2(KDR)/VEGFR3(Flt-4), with IC(50) values of 4nM and 5.2nM respectively.
Product References
  1. Multi-kinase inhibitor E7080 suppresses lymph node and lung metastases of human mammary breast tumor MDA-MB-231 via inhibition of vascular endothelial growth factor-receptor (VEGF-R) 2 and VEGF-R3 kinase: J. Matsui, et al.; Clin. Cancer Res. 14, 5459 (2008)
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