Tandutinib

CHF 60.00
In stock
SYN-1088-M0011 mgCHF 60.00
SYN-1088-M0055 mgCHF 78.00
SYN-1088-M01010 mgCHF 90.00
SYN-1088-M05050 mgCHF 108.00
SYN-1088-M100100 mgCHF 144.00
 
More Information
Product Details
Synonyms CT53518; MLN518
Product Type Chemical
Properties
Formula C31H42N6O4
MW 562.7
CAS 387867-13-2
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO or ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: PDGFR | Kinase Group: RTK | Substrate: Tyrosine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key UXXQOJXBIDBUAC-UHFFFAOYSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Tandutinib inhibits the auto-phosphorylation of FLT3 (FMS-Like Tyrosine kinase-3, IC(50) of 0.22µM), c-KIT and PDGF (platelet-derived growth factor), thereby inhibiting cellular proliferation and inducing apoptosis.
Product References
  1. CT53518, a novel selective FLT3 antagonist for the treatment of acute myelogenous leukemia (AML): L.M. Kelly, et al.; Cancer Cell 1, 421 (2002)
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