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SynKinase
TG101209
CHF 0.00
In stock
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| Product Details | |
|---|---|
| Synonyms | TG-101209 |
| Product Type | Chemical |
| Properties | |
| Formula | C26H35N7O2S |
| MW | 509.7 |
| CAS | 936091-14-4 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO or ethanol. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: JAK2 | Kinase Group: PTK | Substrate: Tyrosine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | JVDOKQYTTYUYDV-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
TG101209 is a potent, small molecule JAK2-selective kinase inhibitor with IC(50) values of 6, 25, 17 and 169nM for JAK2, FLT3, RET and JAK3.
Product References
- TG101209, a small molecule JAK2-selective kinase inhibitor potently inhibits myeloproliferative disorder-associated JAK2V617F and MPLW515L/K mutations: A. Pardanani, et al.; Leukemia 21, 1658 (2007)
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