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SynKinase
R788 disodium salt
CHF 0.00
In stock
SYN-1122-M0011 mgCHF 149.00
SYN-1122-M0055 mgCHF 234.00
SYN-1122-M01010 mgCHF 426.00
SYN-1122-M05050 mgCHF 1'376.00
SYN-1122-M100100 mgINQ
| Product Details | |
|---|---|
| Synonyms | Fostamatinib; Tamatinib fosdium; FosD; R-788 |
| Product Type | Chemical |
| Properties | |
| Formula | C23H24FN6O9P . 2Na |
| MW | 578.5 . 46.0 |
| CAS | 1025687-58-4 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Slightly soluble (<1mg/ml) in DMSO or ethanol. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: BCR | Kinase Group: PTK | Substrate: Tyrosine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | HSYBQXDGYCYSGA-UHFFFAOYSA-L |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
Tamatinib effectively inhibits BCR signaling in vivo, resulting in reduced proliferation and survival of the malignant B cells and significantly prolonged survival of the treated animals.
Product References
- Rational design of highly selective spleen tyrosine kinase inhibitors: M.C. Lucas, et al.; J. Med. Chem. 55, 10414 (2012)
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